SCHEMBL14552158

SCHEMBL14552158

Cc1cccc(N(c2ccccc2)c2ccc(-c3ccc(N(c4ccccc4)c4cccc(C(F)(F)F)c4)c4ccccc34)cc2)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CETP P11597 1/20 0.37
RXRA P19793 1/20 0.34
RXRB P28702 1/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
MAPT P10636 2/20 0.33
RAB9A P51151 2/20 0.33
CKS1B P61024 1/20 0.33
SKP2 Q13309 1/20 0.33
NPC1 O15118 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C19 P33261 1/20 0.33
IDH2 P48735 1/20 0.33
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33
PTPN1 P18031 1/20 0.33
PDK2 Q15119 1/20 0.32
HTT P42858 1/20 0.32
PTPN5 P54829 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14553741 0.93 CKS1B (0.36) CETPRXRARXRBMEN1KMT2A
SCHEMBL7085931 0.89 RXRA (0.41) RXRARXRBMEN1KMT2AMAPT
SCHEMBL7086068 0.89 RXRA (0.41) RXRARXRBMEN1KMT2AMAPT
SCHEMBL14552156 0.89 RXRA (0.41) RXRARXRBMEN1KMT2AMAPT
SCHEMBL16386576 0.84 CETP (0.43) CETPMEN1KMT2AMAPTRAB9A
SCHEMBL14552125 0.84 CETP (0.37) CETPRXRARXRBMAPTRAB9A
SCHEMBL16386585 0.84 CETP (0.38) CETPMEN1KMT2AMAPTRAB9A
SCHEMBL8583893 0.83 CETP (0.46) CETPMEN1KMT2AMAPTRAB9A
SCHEMBL7088898 0.82 SIGMAR1 (0.38) RXRARXRBCYP1A2CYP2C19
SCHEMBL7482902 0.81 HSD17B1 (0.39) MEN1KMT2AMAPTRAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9397294-B2 Vertically phase-separating semiconducting organic material layers SOLVAY USA, INC. (US) 2016-07-19 US disclosed
US-20130009137-A1 VERTICALLY PHASE-SEPARATING SEMICONDUCTING ORGANIC MATERIAL LAYERS PLEXTRONICS, INC. 2013-01-10 US disclosed