Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 2/20 | 0.40 |
| ▸ | TERT | O14746 | 1/20 | 0.40 |
| ▸ | RHEB | Q15382 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10715309 | 0.84 | MAPT (0.54) | ARSCN5ASCN9AALDH1A1SMN1; SMN2 | |
| SCHEMBL30758651 | 0.82 | ALDH1A1 (0.47) | RELAARSCN5ASCN9AALDH1A1 | |
| SCHEMBL23244715 | 0.82 | RELA (0.47) | RELAARSCN5ASCN9AALDH1A1 | |
| SCHEMBL8778154 | 0.82 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2HPGDMEN1MAPT | |
| SCHEMBL7761800 | 0.82 | ALDH1A1 (0.47) | RELAARSCN5ASCN9AALDH1A1 | |
| SCHEMBL3716891 | 0.81 | MAOA (0.52) | ARSCN5ASCN9AALDH1A1SMN1; SMN2 | |
| SCHEMBL29349910 | 0.81 | MAOA (0.52) | ARSCN5ASCN9AALDH1A1SMN1; SMN2 | |
| SCHEMBL6206121 | 0.80 | RHEB (0.52) | ARSCN5ASCN9AALDH1A1SMN1; SMN2 | |
| SCHEMBL29924283 | 0.80 | RHEB (0.52) | ARSCN5ASCN9AALDH1A1SMN1; SMN2 | |
| SCHEMBL5545085 | 0.79 | AR (0.46) | ARSCN5ASCN9AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013006596-A1 | VOLTAGE-GATED SODIUM CHANNEL BLOCKERS | GLAXO GROUP LIMITED (GB) | 2013-01-10 | — | — | WO | disclosed |