Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 1/20 | 0.48 |
| ▸ | SKP1 | P63208 | 1/20 | 0.48 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.48 |
| ▸ | CCNC | P24863 | 1/20 | 0.46 |
| ▸ | CDK8 | P49336 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 5/20 | 0.42 |
| ▸ | CA1 | P00915 | 5/20 | 0.42 |
| ▸ | CA2 | P00918 | 5/20 | 0.42 |
| ▸ | CA9 | Q16790 | 5/20 | 0.42 |
| ▸ | FNTA | P49354 | 2/20 | 0.41 |
| ▸ | FNTB | P49356 | 2/20 | 0.41 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | STK17B | O94768 | 1/20 | 0.40 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14554486 | 0.93 | CKS1B (0.55) | CKS1BSKP1SKP2CCNCCDK8 | |
| SCHEMBL14485496 | 0.84 | SIGMAR1 (0.44) | MGLLTRPV1SCN9A | |
| SCHEMBL14554343 | 0.83 | CKS1B (0.44) | CKS1BSKP1SKP2CCNCCDK8 | |
| SCHEMBL14554497 | 0.80 | CKS1B (0.44) | CKS1BSKP1SKP2CCNCCDK8 | |
| SCHEMBL1937712 | 0.79 | STK17B (0.47) | CA12CA1CA2CA9KCNH2 | |
| SCHEMBL14554636 | 0.77 | CKS1B (0.59) | CKS1BSKP1SKP2CCNCCDK8 | |
| SCHEMBL17858003 | 0.77 | CKS1B (0.52) | CKS1BSKP1SKP2CCNCCDK8 | |
| SCHEMBL14484916 | 0.77 | HCAR3 (0.44) | CKS1BSKP1SKP2EGLN2 | |
| SCHEMBL12185205 | 0.77 | EGLN2 (0.43) | CA12CA1CA2CA9EGLN2 | |
| SCHEMBL14554387 | 0.76 | CKS1B (0.58) | CKS1BSKP1SKP2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013006408-A1 | COMPOUNDS AND METHODS | TEMPERO PHARMACEUTICALS, INC. (US) | 2013-01-10 | — | — | WO | disclosed |