Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 1/20 | 0.58 |
| ▸ | SKP1 | P63208 | 1/20 | 0.58 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.58 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.40 |
| ▸ | STK17B | O94768 | 1/20 | 0.39 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14554636 | 0.86 | CKS1B (0.59) | CKS1BSKP1SKP2TRPV1STK17B | |
| SCHEMBL14554500 | 0.86 | CKS1B (0.56) | CKS1BSKP1SKP2SCN9ATRPV1 | |
| SCHEMBL14554413 | 0.84 | CKS1B (0.57) | CKS1BSKP1SKP2TRPV1STK17B | |
| SCHEMBL14554486 | 0.82 | CKS1B (0.55) | CKS1BSKP1SKP2TRPV1STK17B | |
| SCHEMBL14485788 | 0.82 | HCAR3 (0.47) | CKS1BSKP1SKP2TRPV1DGAT1 | |
| SCHEMBL837529 | 0.80 | CKS1B (0.64) | CKS1BSKP1SKP2POLBCA12 | |
| SCHEMBL16282482 | 0.77 | GRM2 (0.45) | SCN9ASTK17BSTK17APOLBGAA | |
| SCHEMBL14554331 | 0.76 | CKS1B (0.48) | CKS1BSKP1SKP2SCN9ATRPV1 | |
| SCHEMBL30069427 | 0.75 | MAOA (0.46) | SCN9ASTK17BSTK17APOLBGAA | |
| SCHEMBL21744203 | 0.75 | MAOA (0.46) | SCN9ASTK17BSTK17APOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013006408-A1 | COMPOUNDS AND METHODS | TEMPERO PHARMACEUTICALS, INC. (US) | 2013-01-10 | — | — | WO | disclosed |