Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 7/20 | 0.56 |
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | LDHA | P00338 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1848638 | 0.90 | TRPV1 (0.52) | TRPV1RAB9ANPC1CASP3SENP7 | |
| SCHEMBL14079744 | 0.90 | LDHA (0.67) | RAB9ANPC1LDHAPOLBSMN1; SMN2 | |
| SCHEMBL5798843 | 0.82 | RAB9A (0.65) | TRPV1RAB9ANPC1CASP3SENP7 | |
| SCHEMBL5226064 | 0.81 | TRPV1 (0.55) | TRPV1 | |
| SCHEMBL4011536 | 0.80 | LDHA (0.78) | TRPV1RAB9ANPC1CASP3SENP7 | |
| SCHEMBL5226068 | 0.80 | TRPV1 (0.52) | TRPV1 | |
| SCHEMBL10165143 | 0.79 | DYRK1A (0.54) | TRPV1RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL28271344 | 0.78 | CA12 (0.47) | RAB9ANPC1KMT2AMAPTKDM4E | |
| SCHEMBL5782291 | 0.78 | TRPV1 (0.75) | TRPV1RAB9ANPC1CASP3SENP7 | |
| SCHEMBL5383433 | 0.77 | MEN1 (0.61) | RAB9ANPC1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013006408-A1 | COMPOUNDS AND METHODS | TEMPERO PHARMACEUTICALS, INC. (US) | 2013-01-10 | — | — | WO | disclosed |