Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CAMK1D | Q8IU85 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14554401 | 0.78 | HCAR3 (0.41) | SMN1; SMN2HCAR3JAK2PTPN11AOC3 | |
| SCHEMBL2787089 | 0.78 | L3MBTL1 (0.47) | L3MBTL1KDM4ELMNAGAAHTT | |
| SCHEMBL14180516 | 0.77 | L3MBTL1 (0.46) | L3MBTL1KDM4ELMNAGAAHTT | |
| SCHEMBL14554344 | 0.76 | HCAR3 (0.41) | HCAR3TAAR1PTPN11AOC3HRH3 | |
| SCHEMBL14484879 | 0.76 | L3MBTL1 (0.56) | L3MBTL1KDM4ELMNAGAAHTT | |
| SCHEMBL13417452 | 0.73 | GBA1 (0.55) | L3MBTL1KDM4ELMNAGAAHTT | |
| SCHEMBL14554389 | 0.72 | HCAR3 (0.39) | KDM4ELMNAHCAR3TAAR1PTPN11 | |
| SCHEMBL8979076 | 0.71 | L3MBTL1 (0.48) | L3MBTL1KDM4ELMNAGAAHTT | |
| SCHEMBL14554500 | 0.71 | CKS1B (0.56) | L3MBTL1GAAHCAR3TRPV1 | |
| SCHEMBL14554440 | 0.71 | EGLN2 (0.38) | L3MBTL1KDM4ELMNAGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013006408-A1 | COMPOUNDS AND METHODS | TEMPERO PHARMACEUTICALS, INC. (US) | 2013-01-10 | — | — | WO | disclosed |