Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 9/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | TMPRSS15 | P98073 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21669173 | 0.88 | SMN1; SMN2 (0.49) | SMN1; SMN2KEAP1MAPTALDH1A1LMNA | |
| SCHEMBL3752321 | 0.85 | SMN1; SMN2 (0.51) | SMN1; SMN2KEAP1MAPTALDH1A1LMNA | |
| SCHEMBL21638287 | 0.84 | SMN1; SMN2 (0.46) | SMN1; SMN2KEAP1MAPTALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL3753726 | 0.83 | SMN1; SMN2 (0.50) | SMN1; SMN2KEAP1MAPTALDH1A1MEN1 | |
| SCHEMBL4643602 | 0.82 | SMN1; SMN2 (0.49) | SMN1; SMN2KEAP1MAPTALDH1A1MEN1 | |
| SCHEMBL3744447 | 0.81 | LMNA (0.52) | SMN1; SMN2KEAP1MAPTLMNAMEN1 | |
| SCHEMBL3748595 | 0.79 | LMNA (0.50) | SMN1; SMN2KEAP1MAPTALDH1A1LMNA | |
| SCHEMBL19326467 | 0.79 | MAPT (0.51) | SMN1; SMN2KEAP1MAPTALDH1A1LMNA | |
| SCHEMBL3748799 | 0.78 | SMN1; SMN2 (0.44) | SMN1; SMN2KEAP1MAPTALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL3746728 | 0.78 | CYP1A2 (0.51) | SMN1; SMN2KEAP1MAPTLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11161830-B2 | 4-pyridone compound or salt thereof, and pharmaceutical composition and formulation including same | FUJIFILM CORPORATION (JP) | 2021-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11161830-B2 | 4-pyridone compound or salt thereof, and pharmaceutical composition and formulation including same | HAVCR2, HBS1L, PHKB | SMN1; SMN2 4557/4885KEAP1 1858/4885MAPT 2580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.