Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | AR | P10275 | 2/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2754043 | 0.85 | ALDH1A1 (0.55) | RAB9ASMN1; SMN2KDM4ENPC1KMT2A | |
| SCHEMBL2609421 | 0.83 | RAB9A (0.53) | RAB9ASMN1; SMN2KDM4ENPC1KMT2A | |
| SCHEMBL22824711 | 0.83 | MAPT (0.45) | RAB9ASMN1; SMN2KDM4ENPC1KMT2A | |
| SCHEMBL2609415 | 0.81 | RAB9A (0.56) | RAB9ASMN1; SMN2KDM4ENPC1KMT2A | |
| SCHEMBL534352 | 0.81 | PIK3CD (0.38) | RAB9ASMN1; SMN2KDM4ENPC1KMT2A | |
| SCHEMBL2513271 | 0.81 | RAB9A (0.58) | RAB9ASMN1; SMN2KDM4ENPC1KMT2A | |
| SCHEMBL2222772 | 0.81 | ATP4A (0.49) | RAB9ASMN1; SMN2KDM4ENPC1KMT2A | |
| SCHEMBL10052165 | 0.81 | KMT2A (0.58) | RAB9ASMN1; SMN2KDM4ENPC1KMT2A | |
| SCHEMBL12297331 | 0.81 | RAB9A (0.56) | RAB9ASMN1; SMN2KDM4ENPC1KMT2A | |
| SCHEMBL10022327 | 0.81 | CYP19A1 (0.61) | RAB9ASMN1; SMN2KDM4ENPC1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7189728-B2 | Inhibitors of dipeptidyl peptidase IV | FERRING, BV (NL) | 2007-03-13 | — | — | US | disclosed |
| US-7189728-B2 | Inhibitors of dipeptidyl peptidase IV | FERRING, BV (NL) | 2007-03-13 | — | — | US | disclosed |