SCHEMBL14558902

SCHEMBL14558902

N#Cc1c2ccc(C=Cc3ccc(N(c4cccc5ccccc45)c4cccc5ccccc45)cc3)cc2cc2ccc(C=Cc3ccc(N(c4cccc5ccccc45)c4cccc5ccccc45)cc3)cc12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RELA Q04206 1/20 0.35
ALDH1A1 P00352 2/20 0.32
MAPT P10636 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
LMNA P02545 1/20 0.32
POLB P06746 1/20 0.32
HSP90AA1 P07900 1/20 0.32
THRB P10828 1/20 0.32
XBP1 P17861 1/20 0.32
MAPK1 P28482 1/20 0.32
PPARG P37231 1/20 0.32
HTT P42858 1/20 0.32
RECQL P46063 1/20 0.32
RAB9A P51151 1/20 0.32
BLM P54132 1/20 0.32
KMT2A Q03164 1/20 0.32
MCL1 Q07820 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14558907 0.96 RELA (0.36) RELAALDH1A1MAPTSMN1; SMN2KDM4E
SCHEMBL14558904 0.90 NQO2 (0.38) RELAKDM4ENPC1RAB9AAPP
SCHEMBL14079488 0.90 S100A4 (0.34) RELAALDH1A1MAPTSMN1; SMN2KDM4E
SCHEMBL14569481 0.90 S100A4 (0.34) RELAALDH1A1MAPTSMN1; SMN2KDM4E
SCHEMBL14558986 0.87 PTPN2 (0.31)
SCHEMBL14558896 0.86 RELA (0.40) RELAALDH1A1MAPTSMN1; SMN2KDM4E
SCHEMBL14569484 0.85 ALDH1A1 (0.34) RELAALDH1A1MAPTSMN1; SMN2KDM4E
SCHEMBL14079458 0.85 ALDH1A1 (0.34) RELAALDH1A1MAPTSMN1; SMN2KDM4E
SCHEMBL14558987 0.85 PDE9A (0.32)
SCHEMBL12309957 0.84 S100A4 (0.34) RELAALDH1A1MAPTSMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7196225-B2 Bis(aminostyryl) anthracene compound, synthesis intermediate thereof, and process for production thereof SONY CORPORATION (JP) 2007-03-27 US disclosed
US-7196225-B2 Bis(aminostyryl) anthracene compound, synthesis intermediate thereof, and process for production thereof SONY CORPORATION (JP) 2007-03-27 US disclosed