Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | MMP7 | P09237 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | MMP12 | P39900 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | BMP1 | P13497 | 8/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.43 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4928380 | 0.93 | SMN1; SMN2 (0.58) | MMP1MMP7MMP8MMP12MMP13 | |
| SCHEMBL17230532 | 0.78 | BMP1 (0.55) | MMP1MMP7MMP8MMP12MMP13 | |
| SCHEMBL4936946 | 0.78 | SMN1; SMN2 (0.77) | MMP1MMP7MMP8MMP12MMP13 | |
| SCHEMBL6324195 | 0.77 | SMN1; SMN2 (0.65) | MMP1MMP7MMP8MMP12MMP13 | |
| SCHEMBL13979922 | 0.74 | CNR2 (0.61) | MMP1MMP7MMP8MMP12MMP13 | |
| SCHEMBL14229338 | 0.72 | TAS2R14 (0.62) | MMP1MMP7MMP8MMP12MMP13 | |
| SCHEMBL10385428 | 0.72 | BMP1 (0.51) | MMP1MMP7MMP8MMP12MMP13 | |
| SCHEMBL26483278 | 0.71 | MEN1 (0.59) | MMP1MMP7MMP8MMP12MMP13 | |
| SCHEMBL6325862 | 0.70 | BMP1 (0.63) | MMP1MMP7MMP8MMP12MMP13 | |
| SCHEMBL3615482 | 0.70 | BMP1 (0.55) | MMP1MMP7MMP8MMP12MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7186709-B2 | Subjecting a vinyl ethers and an unsaturated ketoester to suitable conditions to generate a scaffold having the core dihydropyrancarboxamide or dihydropyrancarboxylic ester or acid; anticarcinogenic agents | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2007-03-06 | — | — | US | disclosed |
| US-7186709-B2 | Subjecting a vinyl ethers and an unsaturated ketoester to suitable conditions to generate a scaffold having the core dihydropyrancarboxamide or dihydropyrancarboxylic ester or acid; anticarcinogenic agents | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2007-03-06 | — | — | US | disclosed |