Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 6/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 6/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.43 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.39 |
| ▸ | PREP | P48147 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12953666 | 0.86 | GSK3B (0.62) | GSK3B | |
| SCHEMBL12954092 | 0.85 | GSK3B (0.49) | GSK3B | |
| SCHEMBL12953873 | 0.84 | SIGMAR1 (0.47) | TMEM97SIGMAR1AADATFKBP1APREP | |
| SCHEMBL12953756 | 0.75 | GSK3B (0.68) | GSK3B | |
| SCHEMBL12953788 | 0.73 | GSK3B (0.68) | GSK3B | |
| SCHEMBL12953644 | 0.73 | GSK3B (0.62) | GSK3B | |
| SCHEMBL12954320 | 0.72 | GSK3B (0.63) | GSK3B | |
| SCHEMBL14050894 | 0.72 | AADAT (0.48) | TMEM97SIGMAR1AADATFKBP1APREP | |
| SCHEMBL12953650 | 0.71 | GSK3B (0.54) | GSK3B | |
| SCHEMBL12953929 | 0.71 | GSK3B (0.71) | GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7196078-B2 | Trisubstituted and tetrasubstituted pyrazolopyrimidines as cyclin dependent kinase inhibitors | SCHERING CORPOARTION (US) | 2007-03-27 | — | — | US | disclosed |
| US-7196078-B2 | Trisubstituted and tetrasubstituted pyrazolopyrimidines as cyclin dependent kinase inhibitors | SCHERING CORPOARTION (US) | 2007-03-27 | — | — | US | disclosed |