Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 7/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | PREP | P48147 | 2/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12953879 | 0.90 | SIGMAR1 (0.49) | AADATTMEM97SIGMAR1GFERPREP | |
| SCHEMBL12952997 | 0.89 | SIGMAR1 (0.48) | AADATTMEM97SIGMAR1PREP | |
| SCHEMBL14050890 | 0.81 | BCL9 (0.46) | NPSR1MEN1KMT2A | |
| SCHEMBL221048 | 0.81 | AADAT (0.48) | AADATTMEM97SIGMAR1GFERPREP | |
| SCHEMBL28716810 | 0.80 | TMEM97 (0.50) | AADATTMEM97SIGMAR1GFERPREP | |
| SCHEMBL15957792 | 0.79 | SIGMAR1 (0.49) | AADATTMEM97SIGMAR1GFER | |
| SCHEMBL222644 | 0.79 | AADAT (0.48) | AADATTMEM97SIGMAR1GFERFKBP1A | |
| SCHEMBL15513225 | 0.79 | AADAT (0.48) | AADATTMEM97SIGMAR1GFERFKBP1A | |
| SCHEMBL15958257 | 0.77 | AADAT (0.48) | AADATTMEM97SIGMAR1GFERPREP | |
| SCHEMBL15503355 | 0.77 | AADAT (0.47) | AADATTMEM97SIGMAR1GFERFKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008130569-A1 | NOVEL PYRAZOLOPYRIMIDINES AS CYCLIN DEPENDENT KINASE INHIBITORS | SCHERING CORPORATION (US) | 2008-10-30 | — | — | WO | disclosed |