Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 3/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | CCND2 | P30279 | 1/20 | 0.36 |
| ▸ | CCND3 | P30281 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14560417 | 0.78 | CNR2 (0.55) | LMNAADORA3CNR2CNR1SMN1; SMN2 | |
| SCHEMBL14560424 | 0.75 | CNR2 (0.65) | CNR2CNR1ALDH1A1 | |
| SCHEMBL14560598 | 0.73 | MAPT (0.41) | MAPTLMNACNR2CNR1KDM4E | |
| SCHEMBL10767984 | 0.73 | HPGD (0.58) | MAPTSMN1; SMN2TSHR | |
| SCHEMBL20547721 | 0.70 | HPGD (0.55) | MAPTGAASMN1; SMN2TSHR | |
| SCHEMBL11979520 | 0.70 | HPGD (0.55) | MAPTGAASMN1; SMN2TSHR | |
| SCHEMBL29928457 | 0.70 | HPGD (0.55) | MAPTGAASMN1; SMN2TSHR | |
| SCHEMBL22514328 | 0.70 | HPGD (0.55) | MAPTGAASMN1; SMN2TSHR | |
| SCHEMBL11452304 | 0.69 | LMNA (0.39) | LMNAADORA3SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL24481551 | 0.68 | KMT2A (0.63) | LMNASMN1; SMN2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7192967-B1 | Cyclic imide-substituted pyridylalkane, alkene, alkine carboxamides useful as cytostatic and immunosuppressive agents | ASTELLAS PHARMA GMBH (DE) | 2007-03-20 | — | — | US | disclosed |