Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.55 |
| ▸ | CNR1 | P21554 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | CDC25A | P30304 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14560424 | 0.93 | CNR2 (0.65) | CNR2CNR1ALDH1A1CYP19A1CDC25A | |
| SCHEMBL14560505 | 0.81 | CNR2 (0.48) | CNR2CNR1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL14560421 | 0.78 | MAPT (0.48) | CNR2CNR1SMN1; SMN2LMNAADORA3 | |
| SCHEMBL14560604 | 0.77 | CNR2 (0.88) | CNR2CNR1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL11459127 | 0.77 | LMNA (0.71) | CNR2CNR1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL14560410 | 0.76 | CYP19A1 (0.74) | CNR2CNR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL14560487 | 0.75 | ADRA1D (0.56) | SMN1; SMN2MEN1KMT2AALDH1A1CYP19A1 | |
| SCHEMBL18665510 | 0.74 | SMN1; SMN2 (0.50) | CNR2CNR1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL21537191 | 0.74 | CNR2 (0.44) | CNR2CNR1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL14560485 | 0.73 | CYP19A1 (0.56) | CNR2CNR1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7192967-B1 | Cyclic imide-substituted pyridylalkane, alkene, alkine carboxamides useful as cytostatic and immunosuppressive agents | ASTELLAS PHARMA GMBH (DE) | 2007-03-20 | — | — | US | disclosed |