Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.58 |
| ▸ | F2 | P00734 | 1/20 | 0.58 |
| ▸ | PLG | P00747 | 1/20 | 0.58 |
| ▸ | CTSG | P08311 | 1/20 | 0.58 |
| ▸ | CMA1 | P23946 | 1/20 | 0.58 |
| ▸ | CTRC | Q99895 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 2/20 | 0.54 |
| ▸ | BLM | P54132 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14560436 | 0.94 | KMT2A (0.59) | ELANEF2PLGCTSGCMA1 | |
| SCHEMBL23440029 | 0.85 | F2 (0.60) | ELANEF2PLGCTSGCMA1 | |
| SCHEMBL14560444 | 0.84 | CYP19A1 (0.42) | ELANEF2PLGCTSGCMA1 | |
| SCHEMBL13793073 | 0.84 | ELANE (0.82) | ELANEF2PLGCTSGCMA1 | |
| SCHEMBL3419510 | 0.83 | KMT2A (0.80) | ELANEF2PLGCTSGCMA1 | |
| SCHEMBL14560437 | 0.82 | AGTR1 (0.49) | KMT2AMAPTMEN1USP2POLB | |
| SCHEMBL20673341 | 0.81 | F2 (0.64) | ELANEF2PLGCTSGCMA1 | |
| SCHEMBL3422902 | 0.77 | MEN1 (0.86) | ELANEF2PLGCTSGCMA1 | |
| SCHEMBL10159006 | 0.76 | ELANE (0.62) | ELANEF2PLGCTSGCMA1 | |
| SCHEMBL27952145 | 0.75 | HDAC6 (0.54) | ELANEF2PLGCTSGCMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7192967-B1 | Cyclic imide-substituted pyridylalkane, alkene, alkine carboxamides useful as cytostatic and immunosuppressive agents | ASTELLAS PHARMA GMBH (DE) | 2007-03-20 | — | — | US | disclosed |