Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14560433 | 0.82 | ELANE (0.58) | CYP1A2NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL14560436 | 0.77 | KMT2A (0.59) | KMT2AMEN1USP2POLBMAPT | |
| SCHEMBL6968780 | 0.76 | KMT2A (0.55) | CYP1A2CTRB1RAB9AKMT2AMAPT | |
| SCHEMBL14560545 | 0.76 | DRD2 (0.50) | NPC1RAB9ASMN1; SMN2POLBMAPT | |
| SCHEMBL6978776 | 0.76 | KMT2A (0.70) | KMT2AMEN1MAPT | |
| SCHEMBL14560444 | 0.74 | CYP19A1 (0.42) | AGTR1CYP1A2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14560579 | 0.73 | DRD2 (0.48) | NPC1RAB9ASMN1; SMN2POLBMAPT | |
| SCHEMBL2569297 | 0.72 | PABPC1 (0.60) | CYP1A2CTRB1SMN1; SMN2PABPC1ALOX15 | |
| SCHEMBL28752497 | 0.71 | MGLL (0.61) | CYP1A2CYP2A6CTRB1KMT2ADAO | |
| SCHEMBL14560547 | 0.70 | CDC25A (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7192967-B1 | Cyclic imide-substituted pyridylalkane, alkene, alkine carboxamides useful as cytostatic and immunosuppressive agents | ASTELLAS PHARMA GMBH (DE) | 2007-03-20 | — | — | US | disclosed |
| US-7192967-B1 | Cyclic imide-substituted pyridylalkane, alkene, alkine carboxamides useful as cytostatic and immunosuppressive agents | ASTELLAS PHARMA GMBH (DE) | 2007-03-20 | — | — | US | disclosed |