Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | F2 | P00734 | 1/20 | 0.55 |
| ▸ | PLG | P00747 | 1/20 | 0.55 |
| ▸ | ELANE | P08246 | 1/20 | 0.55 |
| ▸ | CTSG | P08311 | 1/20 | 0.55 |
| ▸ | CMA1 | P23946 | 1/20 | 0.55 |
| ▸ | CTRC | Q99895 | 1/20 | 0.55 |
| ▸ | CDC25A | P30304 | 3/20 | 0.50 |
| ▸ | CES1 | P23141 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14560433 | 0.94 | ELANE (0.58) | KMT2AKDM4EMEN1USP2POLB | |
| SCHEMBL3422902 | 0.84 | MEN1 (0.86) | KMT2AKDM4EMEN1USP2POLB | |
| SCHEMBL23440029 | 0.82 | F2 (0.60) | KMT2AKDM4EMEN1USP2POLB | |
| SCHEMBL28256798 | 0.81 | MGLL (0.69) | KMT2AKDM4EMEN1USP2POLB | |
| SCHEMBL13793073 | 0.81 | ELANE (0.82) | KMT2AMEN1MAPTF2PLG | |
| SCHEMBL20673341 | 0.78 | F2 (0.64) | KMT2AKDM4EMEN1USP2MAPT | |
| SCHEMBL14560444 | 0.78 | CYP19A1 (0.42) | KMT2AKDM4EMEN1USP2POLB | |
| SCHEMBL3419510 | 0.77 | KMT2A (0.80) | KMT2AKDM4EMEN1USP2POLB | |
| SCHEMBL14560437 | 0.77 | AGTR1 (0.49) | KMT2AMEN1USP2POLBMAPT | |
| SCHEMBL732925 | 0.76 | CES1 (0.68) | KMT2AMEN1CDC25ACES1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7192967-B1 | Cyclic imide-substituted pyridylalkane, alkene, alkine carboxamides useful as cytostatic and immunosuppressive agents | ASTELLAS PHARMA GMBH (DE) | 2007-03-20 | — | — | US | disclosed |