Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5425511 | 0.84 | CYP1A2 (0.36) | CYP1A2CYP3A4CYP2C9CYP2C19TDP1 | |
| SCHEMBL5425505 | 0.83 | CYP1A2 (0.35) | CYP1A2CYP3A4CYP2C9CYP2C19TDP1 | |
| SCHEMBL14378250 | 0.78 | CYP1A2 (0.53) | CYP1A2CYP3A4CYP2C9CYP2C19TDP1 | |
| SCHEMBL18083203 | 0.77 | APOBEC3A (0.36) | ALDH1A1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL6609431 | 0.72 | GRIA1 (0.33) | ALDH1A1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL17000229 | 0.69 | GRIA1 (0.41) | ALDH1A1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL4366969 | 0.69 | GRIA1 (0.35) | ALDH1A1GRIA1GRIA2GRIA3GRIA4 | |
| Hydrochloric Acid SCHEMBL6613519 | 0.68 | GRIA1 (0.34) | ALDH1A1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL14426993 | 0.67 | CYP1A2 (0.49) | CYP1A2CYP3A4CYP2C9CYP2C19TDP1 | |
| SCHEMBL4373865 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070049594-A1 | Novel compounds and compositions as cathepsin inhibitors | AVENTIS PHARMACEUTICALS INC. (US) | 2007-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070049594-A1 | Novel compounds and compositions as cathepsin inhibitors | CTSS, CTSB, CTSE | CYP1A2 3406/4885CYP3A4 1988/4885CYP2C9 2217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.