Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KDM5C | P41229 | 1/20 | 0.39 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.39 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15797920 | 0.89 | CYP3A4 (0.76) | CYP3A4CYP2C9KCNH2MEN1MAPT | |
| SCHEMBL19474711 | 0.82 | CYP3A4 (0.59) | CYP3A4CYP2C9KCNH2L3MBTL1CYP2C19 | |
| SCHEMBL27097987 | 0.79 | CYP3A4 (1.00) | CYP3A4CYP2C9KCNH2KDM4E | |
| SCHEMBL6254551 | 0.76 | CYP3A4 (0.50) | CYP3A4CYP2C9KCNH2MAPTKDM4E | |
| SCHEMBL15346036 | 0.76 | CYP3A4 (0.60) | CYP3A4CYP2C9KCNH2MEN1MAPT | |
| SCHEMBL5318616 | 0.76 | KCNH2 (0.52) | CYP3A4CYP2C9KCNH2CYP1A2MEN1 | |
| SCHEMBL12198281 | 0.74 | CYP3A4 (0.48) | CYP3A4CYP2C9KCNH2MEN1MAPT | |
| SCHEMBL25395337 | 0.73 | CYP3A4 (0.83) | CYP3A4CYP2C9KCNH2CYP1A2KDM4E | |
| SCHEMBL15362803 | 0.73 | CYP3A4 (0.50) | CYP3A4CYP2C9KCNH2L3MBTL1CYP1A2 | |
| SCHEMBL30117644 | 0.73 | ALDH1A1 (0.53) | CYP3A4CYP2C9KCNH2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070066672-A1 | Benzimidazole derivatives and use thereof as peptide deformylase inhibitors | ARPIDA A/S (DK) | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066672-A1 | Benzimidazole derivatives and use thereof as peptide deformylase inhibitors | PDF, MRPL21, PEPD | CYP3A4 1956/4885CYP2C9 2307/4885KCNH2 4477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.