⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1184 | 0.77 | — | — | |
| SCHEMBL9766990 | 0.76 | HTT (0.43) | — | |
| SCHEMBL7770871 | 0.76 | — | — | |
| SCHEMBL9767135 | 0.76 | HTT (0.43) | — | |
| SCHEMBL10755222 | 0.74 | OR51E2 (0.38) | — | |
| SCHEMBL12265167 | 0.73 | — | — | |
| SCHEMBL9321078 | 0.71 | HTT (0.51) | — | |
| SCHEMBL9767447 | 0.71 | HTT (0.51) | — | |
| SCHEMBL9767019 | 0.69 | HTT (0.57) | — | |
| SCHEMBL9767015 | 0.67 | HTT (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6686321-B2 | MIXTURE; LUBRICANT OIL ADDITIVE | CASTROL LIMITED (GB) | 2004-02-03 | — | — | US | claimed |
| US-5008402-A | Reacting a 3-pyrrolin-2-one with an aldehyde or ketone; hydrogenating | LONZA LTD. (CH) | 1991-04-16 | — | — | US | claimed |
| US-12545640-B2 | Substituted 6,7-dihydro-5H-benzo[7]annulene compounds, processes for their preparation and therapeutic uses thereof | SANOFI (FR) | 2026-02-10 | — | — | US | disclosed |
| US-20250236619-A1 | FUSED BICYCLIC COMPOUND CONTAINING PYRROLINONE | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2025-07-24 | — | — | US | disclosed |
| CN-119768472-A | Resin composition, cured film, and semiconductor device | 东丽株式会社 | 2025-04-04 | — | — | CN | disclosed |
| US-20250034149-A1 | DIHYDROPYRROLO[3,4C]-PYRAZOLE DERIVATIVES AND THEIR USE IN DIAGNOSIS | AC IMMUNE SA (CH) | 2025-01-30 | — | — | US | disclosed |
| EP-4484434-A1 | FUSED BICYCLIC COMPOUND CONTAINING PYRROLINONE | Chia Tai Tianqing Pharmaceutical Group Co., Ltd (CN) | 2025-01-01 | — | — | EP | disclosed |
| EP-4430045-A1 | DIHYDROPYRROLO[3,4C]-PYRAZOLE DERIVATIVES AND THEIR USE IN DIAGNOSIS | AC Immune SA (CH) | 2024-09-18 | — | — | EP | disclosed |
| CN-118510781-A | Dihydropyrrolo [3,4C ] -pyrazole derivatives and their use in diagnosis | AC免疫有限公司 | 2024-08-16 | — | — | CN | disclosed |
| WO-2024070387-A1 | RESIN COMPOSITION, CURED FILM, AND SEMICONDUCTOR DEVICE | 東レ株式会社 | 2024-04-04 | — | — | WO | disclosed |
| CN-117177974-A | Imidazole-containing condensed ring derivative, preparation method and medical application thereof | 长春金赛药业有限责任公司 | 2023-12-05 | — | — | CN | disclosed |
| US-4855451-A | 4-benzyloxy-3-pyrrolin-2-one, its production and use for synthesis of tetramic acid | LONZA LTD. (CH) | 1989-08-08 | — | — | US | disclosed |
| US-4849528-A | 4-HYDROXYPYRROLIDIN-2-ON-1-YLACETAMIDE, INTERMEDIATE | LONZA LTD. (CH) | 1989-07-18 | — | — | US | disclosed |
| US-4843166-A | 4-benzyloxy-3-pyrrolin-2-on-1-yl acetamide production | LONZA LTD. (CH) | 1989-06-27 | — | — | US | disclosed |
| US-4812578-A | Synthesis of tetramic acid | LONZA LTD. (CH) | 1989-03-14 | — | — | US | disclosed |
| US-4788294-A | Process for the production of 4-alkoxy-3-pyrrolin-2-ones | LONZA LTD. (CH) | 1988-11-29 | — | — | US | disclosed |
| US-4780545-A | Production of 4-alkoxy-3-pyrrolin-2-on-1-yl acetic acid alkyl esters | LONZA LTD. (CH) | 1988-10-25 | — | — | US | disclosed |
| EP-0252363-A1 | 4-Benzyloxy-3-pyrrolin-2-one, preparation and use in the synthesis of 2,4-pyrrolidinedione | LONZA AG (CH) | 1988-01-13 | — | — | EP | disclosed |
| EP-0252353-A1 | 4-Benzyloxy-3-pyrrolin-2-one-1-yl-acetamide, preparation and use | LONZA AG (CH) | 1988-01-13 | — | — | EP | disclosed |
| EP-0216324-A2 | 4-Alkoxy-3-pyrrolin-2-one-1-yl-acetic acid alkyl and benzyl esters and their preparation | LONZA AG (CH) | 1987-04-01 | — | — | EP | disclosed |