⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9766935 | 0.86 | HTT (0.54) | — | |
| SCHEMBL9767275 | 0.84 | HTT (0.53) | — | |
| SCHEMBL9321078 | 0.82 | HTT (0.51) | — | |
| SCHEMBL9767272 | 0.81 | HTT (0.50) | — | |
| SCHEMBL9767026 | 0.81 | HTT (0.50) | — | |
| SCHEMBL9685442 | 0.80 | HTT (0.38) | — | |
| SCHEMBL9767447 | 0.79 | HTT (0.51) | — | |
| SCHEMBL3103319 | 0.77 | PARP1 (0.38) | — | |
| SCHEMBL9767347 | 0.76 | HTT (0.53) | — | |
| SCHEMBL31680983 | 0.76 | FKBP5 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022023839-A1 | 2-(2-OXO-3-PYROLIN-1-YL)ACETAMIDES AS ANTICONVULSANTS | LATVIAN INSTITUTE OF ORGANIC SYNTHESIS (LV) | 2022-02-03 | — | — | WO | disclosed |
| EP-0909271-B1 | INDOLYL-PYRROLYDENEMETHYLPYRROLE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | PHARMACIA & UPJOHN SPA (IT) | 2001-09-26 | — | — | EP | disclosed |
| EP-0825983-B1 | PROCESS FOR THE PREPARATION OF 2,2'-BIPYRROLYL-PYRROMETHENE (PRODIGIOSINS) DERIVATIVES | PHARMACIA & UPJOHN SPA (IT) | 2001-08-29 | — | — | EP | disclosed |
| US-6071947-A | IMMUNOSUPPRESSANT AND ANTIINFLAMMATORY AGENTS FOR TREATMENT OF TRANSPLANT REJECTION, AUTOIMMUNE OR RHEUMATIC DISORDERS, VIRAL DISEASES | PHARMACIA & UPJOHN S.P.A. (IT) | 2000-06-06 | — | — | US | disclosed |
| EP-0909271-A1 | INDOLYL-PYRROLYDENEMETHYLPYRROLE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | PHARMACIA & UPJOHN S.p.A. (IT) | 1999-04-21 | — | — | EP | disclosed |
| US-5847127-A | Process for the preparation of 2,2'-bipyrrolyl-pyrromethene (prodigiosins) derivatives | PHARMACIA & UPJOHN S.P.A. (IT) | 1998-12-08 | — | — | US | disclosed |
| WO-1998040380-A1 | INDOLYL-PYRROLYDENEMETHYLPYRROLE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | PHARMACIA & UPJOHN S.P.A. (IT) | 1998-09-17 | — | — | WO | disclosed |
| EP-0825983-A1 | PROCESS FOR THE PREPARATION OF 2,2'-BIPYRROLYL-PYRROMETHENE (PRODIGIOSINS) DERIVATIVES | PHARMACIA & UPJOHN S.p.A. (IT) | 1998-03-04 | — | — | EP | disclosed |
| WO-1997030029-A1 | PROCESS FOR THE PREPARATION OF 2,2'-BIPYRROLYL-PYRROMETHENE (PRODIGIOSINS) DERIVATIVES | PHARMACIA & UPJOHN S.P.A. (IT) | 1997-08-21 | — | — | WO | disclosed |
| US-5072006-A | Chemical intermeidate; hypotensive agents, muscle relaxants | RECHERCHE SYNTEX FRANCE S.A. (FR) | 1991-12-10 | — | — | US | disclosed |
| US-4997846-A | Smooth muscle relaxants, hypotensives | RESEARCHE SYNTEX FRANCE, S.A. (FR) | 1991-03-05 | — | — | US | disclosed |
| EP-0377966-A2 | Novel benzopyranylpyrrolinone derivatives | RECHERCHE SYNTEX FRANCE SA (FR) | 1990-07-18 | — | — | EP | disclosed |