Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 5/20 | 0.56 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.52 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.52 |
| ▸ | ITGAL | P20701 | 3/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.49 |
| ▸ | HPGDS | O60760 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14565635 | 0.92 | HPGDS (0.55) | NAMPTITGB2ICAM1ITGALCTSL | |
| SCHEMBL14565637 | 0.91 | NAMPT (0.53) | NAMPTCTSLCTSBCTSSCTSK | |
| SCHEMBL14565638 | 0.90 | NAMPT (0.69) | NAMPTITGB2ICAM1ITGALERAP2 | |
| SCHEMBL14565640 | 0.82 | NAMPT (0.68) | NAMPTITGB2ICAM1ITGALERAP2 | |
| SCHEMBL14565639 | 0.81 | NAMPT (0.66) | NAMPTITGB2ICAM1ITGALERAP2 | |
| SCHEMBL10805861 | 0.77 | ITGB2 (0.64) | ITGB2ICAM1ITGALCTSLCTSB | |
| SCHEMBL16617786 | 0.77 | ITGB2 (0.64) | ITGB2ICAM1ITGALCTSLCTSB | |
| SCHEMBL14565644 | 0.77 | ERAP2 (0.72) | ITGB2ICAM1ITGALERAP2ALOX15 | |
| SCHEMBL14581324 | 0.76 | CTSL (0.48) | CTSLCTSBCTSSCTSKHPGDS | |
| SCHEMBL14581323 | 0.76 | CTSL (0.48) | CTSLCTSBCTSSCTSKHPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7189724-B2 | Quinoxaline derivatives having antiviral activity | VALEANT RESEARCH AND DEVELOPMENT (US) | 2007-03-13 | — | — | US | disclosed |
| US-7189724-B2 | Quinoxaline derivatives having antiviral activity | VALEANT RESEARCH AND DEVELOPMENT (US) | 2007-03-13 | — | — | US | disclosed |