Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 15/20 | 0.49 |
| ▸ | CTSL | P07711 | 12/20 | 0.49 |
| ▸ | CTSS | P25774 | 8/20 | 0.49 |
| ▸ | CTSB | P07858 | 6/20 | 0.49 |
| ▸ | CTSV | O60911 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PKLR | P30613 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14565729 | 0.82 | PKM (0.46) | PKM | |
| SCHEMBL5105578 | 0.81 | CTSK (0.55) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL5105546 | 0.80 | CTSK (0.53) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL5105583 | 0.80 | CTSK (0.57) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL8336654 | 0.80 | CTSK (0.45) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4768241 | 0.80 | CTSK (0.45) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL14565745 | 0.80 | CCND1 (0.35) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL14565738 | 0.79 | KMT2A (0.48) | — | |
| SCHEMBL7429565 | 0.79 | CTSK (0.55) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL7588951 | 0.79 | CTSK (0.57) | CTSKCTSLCTSSCTSBCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7196099-B2 | Compounds and compositions as cathepsin inhibitors | AVENTIS PHARMACEUTICALS INC. (US) | 2007-03-27 | — | — | US | disclosed |