Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 3/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14565738 | 0.84 | KMT2A (0.48) | LMNAALDH1A1GAAMEN1KMT2A | |
| SCHEMBL14565727 | 0.84 | PKM (0.43) | PKMALDH1A1MEN1KMT2AHTR6 | |
| SCHEMBL14565737 | 0.82 | RAB9A (0.47) | KDM4EMEN1KMT2A | |
| SCHEMBL14565743 | 0.82 | MEN1 (0.55) | SMN1; SMN2MEN1KMT2ADRD2 | |
| SCHEMBL14565734 | 0.82 | CTSK (0.49) | PKM | |
| SCHEMBL14565740 | 0.81 | ATM (0.47) | PKMALDH1A1GAAKDM4E | |
| SCHEMBL14565744 | 0.81 | PKM (0.49) | PKMALDH1A1GAAKDM4EMEN1 | |
| SCHEMBL14565739 | 0.79 | GPBAR1 (0.56) | LMNAALDH1A1GAASMN1; SMN2MEN1 | |
| SCHEMBL14565751 | 0.79 | TSHR (0.36) | LMNAALDH1A1GAASMN1; SMN2MEN1 | |
| SCHEMBL14565752 | 0.78 | POLB (0.37) | LMNAALDH1A1GAAKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7196099-B2 | Compounds and compositions as cathepsin inhibitors | AVENTIS PHARMACEUTICALS INC. (US) | 2007-03-27 | — | — | US | disclosed |