Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.76 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.66 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.66 |
| ▸ | EGFR | P00533 | 1/20 | 0.56 |
| ▸ | ERN1 | O75460 | 5/20 | 0.56 |
| ▸ | RXRA | P19793 | 6/20 | 0.55 |
| ▸ | RXRB | P28702 | 5/20 | 0.55 |
| ▸ | RXRG | P48443 | 2/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.50 |
| ▸ | BAD | Q92934 | 1/20 | 0.50 |
| ▸ | UNG | P13051 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16102962 | 1.00 | ALDH1A1 (0.76) | ALDH1A1TRIM24TRIM33EGFRERN1 | |
| SCHEMBL14565866 | 1.00 | ALDH1A1 (0.76) | ALDH1A1TRIM24TRIM33EGFRERN1 | |
| SCHEMBL1124585 | 0.94 | ALDH1A1 (0.86) | ALDH1A1TRIM24TRIM33ERN1RXRA | |
| SCHEMBL12212911 | 0.94 | ALDH1A1 (0.86) | ALDH1A1TRIM24TRIM33ERN1RXRA | |
| SCHEMBL12212906 | 0.94 | ALDH1A1 (0.86) | ALDH1A1TRIM24TRIM33ERN1RXRA | |
| SCHEMBL12212915 | 0.94 | ALDH1A1 (0.86) | ALDH1A1TRIM24TRIM33ERN1RXRA | |
| SCHEMBL31532963 | 0.92 | TRIM24 (0.71) | ALDH1A1TRIM24TRIM33EGFRERN1 | |
| SCHEMBL17090378 | 0.88 | ALDH1A1 (0.59) | ALDH1A1TRIM24TRIM33EGFRERN1 | |
| Terephthalic Acid SCHEMBL11068404 | 0.87 | ALDH1A1 (1.00) | ALDH1A1TRIM24TRIM33UNGTP53 | |
| SCHEMBL63361 | 0.87 | ALDH1A1 (1.00) | ALDH1A1TRIM24TRIM33UNGTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8946454-B2 | Chemical framework compositions and methods of use | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-02-03 | — | — | US | disclosed |
| US-20070068389-A1 | Metal-organic frameworks with exceptionally high capacity for storage of carbon dioxide at room-temperature | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2007-03-29 | — | — | US | disclosed |