SCHEMBL1124585

SCHEMBL1124585

O=Cc1ccc(-c2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.86

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.86
TRIM24 O15164 1/20 0.67
TRIM33 Q9UPN9 1/20 0.67
ERN1 O75460 3/20 0.56
BCL2L1 Q07817 1/20 0.56
BAD Q92934 1/20 0.56
TP53 P04637 1/20 0.55
TSHR P16473 1/20 0.55
KMT2A Q03164 1/20 0.52
TDP1 Q9NUW8 2/20 0.52
KDM4E B2RXH2 1/20 0.52
RXRA P19793 2/20 0.50
RXRB P28702 2/20 0.50
UNG P13051 1/20 0.50
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA9 Q16790 1/20 0.48
CA14 Q9ULX7 1/20 0.48
GLA P06280 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12212906 1.00 ALDH1A1 (0.86) ALDH1A1TRIM24TRIM33ERN1BCL2L1
SCHEMBL12212911 1.00 ALDH1A1 (0.86) ALDH1A1TRIM24TRIM33ERN1BCL2L1
SCHEMBL12212915 1.00 ALDH1A1 (0.86) ALDH1A1TRIM24TRIM33ERN1BCL2L1
SCHEMBL14565866 0.94 ALDH1A1 (0.76) ALDH1A1TRIM24TRIM33ERN1BCL2L1
SCHEMBL16102962 0.94 ALDH1A1 (0.76) ALDH1A1TRIM24TRIM33ERN1BCL2L1
SCHEMBL14565804 0.94 ALDH1A1 (0.76) ALDH1A1TRIM24TRIM33ERN1BCL2L1
Terephthalic Acid SCHEMBL11068404 0.93 ALDH1A1 (1.00) ALDH1A1TRIM24TRIM33TP53TSHR
SCHEMBL63361 0.93 ALDH1A1 (1.00) ALDH1A1TRIM24TRIM33TP53TSHR
SCHEMBL8161786 0.91 ALDH1A1 (0.95) ALDH1A1TRIM24TRIM33TP53TSHR
Hydrochloric Acid SCHEMBL740726 0.91 ALDH1A1 (0.95) ALDH1A1TRIM24TRIM33TP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115677864-B Cellulose coumarin fluorescent probe for detecting cyanide ions and preparation method and application thereof 南京林业大学 2023-08-29 CN claimed
CN-115677864-A Cellulose-based coumarin fluorescent probe for detecting cyanide ions and preparation method and application thereof 南京林业大学 2023-02-03 CN claimed
US-20180282257-A1 Aromatic Monoester Compositions and Processes for Preparing Same EXXONMOBIL CHEMICAL PATENTS INC. 2018-10-04 US claimed
US-20260078105-A1 Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors ORSOBIO INC (US) 2026-03-19 US disclosed
CN-114933660-B Cellulose-based coumarin fluorescent probe for detecting hydrazine and preparation method and application thereof 南京林业大学 2023-04-11 CN disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
EP-3327001-B1 NOVEL COMPOUND HAVING BLT INHIBITORY ACTIVITY AND COMPOSITION, FOR PREVENTING OR TREATING INFLAMMATORY DISEASES, COMPRISING SAME AS ACTIVE INGREDIENT UNIV DONGGUK IND ACAD COOP (KR) 2022-04-13 EP disclosed
US-20200361845-A1 Preparation and Use of Biphenyldicarboxylic Acids EXXONMOBIL CHEMICAL PATENTS INC. 2020-11-19 US disclosed
US-20200290945-A1 Preparation and Purification of Biphenyldicarboxylic Acids EXXONMOBIL CHEMICAL PATENTS INC (US) 2020-09-17 US disclosed
US-10774212-B2 Thermally conductive material, resin composition, and device FUJIFILM CORPORATION (JP) 2020-09-15 US disclosed
US-10322991-B2 Selective aerobic oxidation of dimethylbiphenyls EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2019-06-18 US disclosed
EP-2284157-A1 Quinolines useful in treating cardiovascular disease Wyeth (US) 2011-02-16 EP disclosed
US-20100190766-A1 ANTIBACTERIAL AGENTS ACHAOGEN, INC. (US) 2010-07-29 US disclosed
US-20100036138-A1 CATALYST AND METHOD FOR PRODUCING CARBOXYLIC ACID AND/OR CARBOXYLIC ANHYDRIDE IN THE PRESENCE OF THE CATALYST MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2010-02-11 US disclosed
EP-2135671-A2 Catalyst and method for producing carboxylic acid and/or carboxylic anhydride in the presence of the catalyst Mitsubishi Gas Chemical Company, Inc. (JP) 2009-12-23 EP disclosed
US-7576215-B2 Quinolines and pharmaceutical compositions thereof WYETH (US) 2009-08-18 US disclosed
WO-2008154642-A2 ANTIBACTERIAL AGENTS ACHAOGEN, INC. (US) 2008-12-18 WO disclosed
EP-1692111-A2 QUINOLINES USEFUL IN TREATING CARDIOVASCULAR DISEASE Wyeth, A Corporation of the State of Delaware (US) 2006-08-23 EP disclosed
WO-2005058834-A2 QUINOLINES USEFUL IN TREATING CARDIOVASCULAR DISEASE WYETH (US) 2005-06-30 WO disclosed
US-20050131014-A1 Quinolines useful in treating cardiovascular disease WYETH (US) 2005-06-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200290945-A1 Preparation and Purification of Biphenyldicarboxylic Acids DDC, MCCC2, ADH1C ALDH1A1 257/4885TRIM24 764/4885TRIM33 767/4885
US-20260078105-A1 Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors CPT1B, CBR1, MUSK ALDH1A1 290/4885TRIM24 1098/4885TRIM33 1600/4885
US-20200361845-A1 Preparation and Use of Biphenyldicarboxylic Acids BBOX1, DDT, DDC ALDH1A1 1020/4885TRIM24 1304/4885TRIM33 3042/4885
US-20100190766-A1 ANTIBACTERIAL AGENTS MRPL21, SI, ABCB11 ALDH1A1 687/4885TRIM24 3995/4885TRIM33 4245/4885
US-10322991-B2 Selective aerobic oxidation of dimethylbiphenyls MSMO1, CYP1B1, CYP1A1 ALDH1A1 58/4885TRIM24 1198/4885TRIM33 2509/4885
US-20050131014-A1 Quinolines useful in treating cardiovascular disease NR1H2, NR1H3, SREBF1 ALDH1A1 1202/4885TRIM24 1957/4885TRIM33 3226/4885
US-20180282257-A1 Aromatic Monoester Compositions and Processes for Preparing Same ADH1A, ADH1C, GK ALDH1A1 142/4885TRIM24 1148/4885TRIM33 385/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.