SCHEMBL17090378

SCHEMBL17090378

O=Cc1ccc(-c2cc(-c3ccc(C(=O)O)cc3)cc(-c3ccc(C(=O)OO)cc3)c2)cc1

nearest known ligand 0.59

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.59
TRIM24 O15164 1/20 0.54
TRIM33 Q9UPN9 1/20 0.54
ERN1 O75460 5/20 0.49
BCL2L1 Q07817 1/20 0.49
BAD Q92934 1/20 0.49
EGFR P00533 1/20 0.46
RXRA P19793 6/20 0.45
RXRB P28702 5/20 0.45
RXRG P48443 2/20 0.41
PARP10 Q53GL7 1/20 0.41
PARP3 Q9Y6F1 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14565804 0.88 ALDH1A1 (0.76) ALDH1A1TRIM24TRIM33ERN1BCL2L1
SCHEMBL14565866 0.88 ALDH1A1 (0.76) ALDH1A1TRIM24TRIM33ERN1BCL2L1
SCHEMBL16102962 0.88 ALDH1A1 (0.76) ALDH1A1TRIM24TRIM33ERN1BCL2L1
SCHEMBL14140029 0.88 ALDH1A1 (0.60) ALDH1A1TRIM24TRIM33ERN1BCL2L1
SCHEMBL12212911 0.83 ALDH1A1 (0.86) ALDH1A1TRIM24TRIM33ERN1BCL2L1
SCHEMBL12212906 0.83 ALDH1A1 (0.86) ALDH1A1TRIM24TRIM33ERN1BCL2L1
SCHEMBL1124585 0.83 ALDH1A1 (0.86) ALDH1A1TRIM24TRIM33ERN1BCL2L1
SCHEMBL12212915 0.83 ALDH1A1 (0.86) ALDH1A1TRIM24TRIM33ERN1BCL2L1
SCHEMBL29139554 0.83 BCL2L1 (0.68) BCL2L1BADEGFRRXRARXRB
SCHEMBL31532963 0.81 TRIM24 (0.71) ALDH1A1TRIM24TRIM33ERN1BCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9139601-B2 Crystallisation facilitators for the synthesis of metal organic frameworks COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2015-09-22 US disclosed