Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAPDH | P04406 | 2/20 | 0.49 |
| ▸ | PTPRC | P08575 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | P4HB | P07237 | 1/20 | 0.44 |
| ▸ | ILF3 | Q12906 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 2/20 | 0.37 |
| ▸ | CASP7 | P55210 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Bromo-1,4-Naphthoquinone SCHEMBL29633250 | 0.79 | PTPRC (0.68) | GAPDHPTPRCMEN1KMT2AMAPK1 | |
| 2-Bromo-1,4-Naphthoquinone SCHEMBL312893 | 0.79 | PTPRC (0.68) | GAPDHPTPRCMEN1KMT2AMAPK1 | |
| SCHEMBL31744557 | 0.76 | GAPDH (0.49) | GAPDHPTPRCMEN1KMT2AMAPK1 | |
| SCHEMBL8661355 | 0.76 | GAPDH (0.49) | GAPDHPTPRCMEN1KMT2AMAPK1 | |
| SCHEMBL6683984 | 0.76 | GAPDH (0.49) | GAPDHMEN1KMT2AMAPK1MAPT | |
| SCHEMBL10446178 | 0.76 | ALDH1A1 (0.64) | GAPDHMEN1KMT2AMAPK1MAPT | |
| SCHEMBL29364188 | 0.75 | MEN1 (0.56) | GAPDHPTPRCMEN1KMT2AMAPK1 | |
| SCHEMBL354514 | 0.75 | MEN1 (0.56) | GAPDHPTPRCMEN1KMT2AMAPK1 | |
| SCHEMBL30130196 | 0.75 | MEN1 (0.56) | GAPDHPTPRCMEN1KMT2AMAPK1 | |
| Acridine SCHEMBL28153648 | 0.74 | PTPRC (0.46) | PTPRCMEN1KMT2AMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007026041-A2 | COMPUESTOS QUINÓNICOS ANTITUMORALES Y SUS DERIVADOS, PROCEDIMIENTO DE OBTENCIÓN Y SUS APLICACIONES | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) | 2007-03-08 | — | — | WO | disclosed |