Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | GUSB | P08236 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | MAOB | P27338 | 4/20 | 0.52 |
| ▸ | MAOA | P21397 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | VCP | P55072 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14865149 | 0.93 | PTGS2 (0.69) | PTGS2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL8245332 | 0.91 | PTGS2 (0.64) | PTGS2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL16742058 | 0.80 | GUSB (0.64) | PTGS2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL16742057 | 0.80 | GUSB (0.64) | PTGS2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL14233890 | 0.77 | PTGS2 (0.56) | PTGS2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL15952677 | 0.77 | PTGS2 (0.56) | PTGS2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL15952679 | 0.77 | PTGS2 (0.56) | PTGS2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL22811133 | 0.75 | PTGS2 (0.45) | PTGS2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL12443462 | 0.74 | MEN1 (0.72) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL14126972 | 0.74 | PTGS2 (0.53) | PTGS2MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070060526-A1 | Methods of facilitating neural cell survival using non-peptide and peptide BDNF neurotrophin mimetics | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060526-A1 | Methods of facilitating neural cell survival using non-peptide and peptide BDNF neurotrophin mimetics | BDNF, NTRK2, NGF | PTGS2 3390/4885MEN1 3566/4885KMT2A 3874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.