Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 11/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.45 |
| ▸ | DPP4 | P27487 | 5/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.45 |
| ▸ | FAP | Q12884 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.38 |
| ▸ | GSR | P00390 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7694263 | 0.73 | DPP7 (0.54) | DPP7DPP8DPP4DPP9FAP | |
| SCHEMBL23930646 | 0.72 | DPP7 (0.47) | DPP7DPP8DPP4DPP9FAP | |
| SCHEMBL6234583 | 0.71 | DPP7 (0.48) | DPP7DPP8DPP4DPP9FAP | |
| SCHEMBL6234578 | 0.71 | DPP7 (0.48) | DPP7DPP8DPP4DPP9FAP | |
| SCHEMBL2113409 | 0.69 | DPP7 (0.65) | DPP7DPP8DPP4DPP9FAP | |
| SCHEMBL2123083 | 0.69 | DPP7 (0.65) | DPP7DPP8DPP4DPP9FAP | |
| SCHEMBL2113410 | 0.69 | DPP7 (0.65) | DPP7DPP8DPP4DPP9FAP | |
| SCHEMBL29374265 | 0.69 | DPP7 (0.65) | DPP7DPP8DPP4DPP9FAP | |
| SCHEMBL29406923 | 0.69 | DPP7 (0.65) | DPP7DPP8DPP4DPP9FAP | |
| SCHEMBL2123080 | 0.69 | DPP7 (0.65) | DPP7DPP8DPP4DPP9FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120258960-A1 | NOVEL MULTIFUNCTIONAL PEPTIDASE INHIBITORS, ESPECIALLY FOR MEDICAL USE | IMTM GMBH (DE) | 2012-10-11 | — | — | US | disclosed |
| EP-2292589-A1 | Novel multifunctional peptidase inhibitors, especially for medical use | IMTM GmbH (DE) | 2011-03-09 | — | — | EP | disclosed |
| US-7816325-B2 | Secondary binding site of dipeptidyl peptidase IV (DP IV) | OSI PHARMACEUTICALS, INC. (US) | 2010-10-19 | — | — | US | disclosed |
| WO-2010072327-A2 | PHARMACEUTICAL COMPOSITION BASED ON PEPTIDE FROM CAMEL MILK | KAMAMED GMBH (DE) | 2010-07-01 | — | — | WO | disclosed |
| EP-1543023-B1 | SECONDARY BINDING SITE OF DIPEPTIDYL PEPTIDASE IV (DP IV) | PROSIDION LTD (GB) | 2010-03-17 | — | — | EP | disclosed |
| US-20060234940-A1 | Secondary binding site of dipeptidyl peptidase IV (DP IV) | ROYALTY PHARMA FINANCE TRUST | 2006-10-19 | — | — | US | disclosed |
| US-20050176622-A1 | Secondary binding site of dipeptidyl peptidase IV (DPIV) | PROSIDION LIMITED (GB) | 2005-08-11 | — | — | US | disclosed |
| EP-1543023-A2 | SECONDARY BINDING SITE OF DIPEPTIDYL PEPTIDASE IV (DP IV) | Prosidion Limited (GB) | 2005-06-22 | — | — | EP | disclosed |
| WO-2004031374-A2 | SECONDARY BINDING SITE OF DIPEPTIDYL PEPTIDASE IV (DP IV) | PROSIDION LTD. (GB) | 2004-04-15 | — | — | WO | disclosed |
| US-20040058876-A1 | Secondary binding site of dipeptidyl peptidase IV (DP IV) | PROSIDION LIMITED (GB) | 2004-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060234940-A1 | Secondary binding site of dipeptidyl peptidase IV (DP IV) | DPP4, DPP3, DPP7 | DPP7 3/4885DPP8 4/4885DPP4 1/4885 |
| US-20040058876-A1 | Secondary binding site of dipeptidyl peptidase IV (DP IV) | DPP4, DPP3, DPP7 | DPP7 3/4885DPP8 4/4885DPP4 1/4885 |
| US-20050176622-A1 | Secondary binding site of dipeptidyl peptidase IV (DPIV) | DPP4, DPP3, DPP7 | DPP7 3/4885DPP8 4/4885DPP4 1/4885 |
| US-20120258960-A1 | NOVEL MULTIFUNCTIONAL PEPTIDASE INHIBITORS, ESPECIALLY FOR MEDICAL USE | PEPD, CTSC, SERPINB1 | DPP7 15/4885DPP8 32/4885DPP4 19/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.