SCHEMBL6234583

SCHEMBL6234583

NCCCC[C@H](N)C(=O)C1CCN1C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 14/20 0.48
GSR P00390 1/20 0.47
DPP8 Q6V1X1 7/20 0.47
DPP4 P27487 6/20 0.47
DPP9 Q86TI2 5/20 0.47
FAP Q12884 1/20 0.47
ITGB3 P05106 2/20 0.39
ITGA2B P08514 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6234578 1.00 DPP7 (0.48) DPP7GSRDPP8DPP4DPP9
SCHEMBL6234680 0.95 DPP7 (0.42) DPP7GSRDPP8DPP4DPP9
SCHEMBL6234685 0.95 DPP7 (0.42) DPP7GSRDPP8DPP4DPP9
SCHEMBL6236988 0.82 ACE (0.39) DPP7GSRDPP8DPP4DPP9
SCHEMBL6236016 0.81 DPP4 (0.47) DPP7GSRDPP8DPP4DPP9
SCHEMBL6236019 0.81 DPP4 (0.47) DPP7GSRDPP8DPP4DPP9
SCHEMBL6236993 0.81 DPP7 (0.34) DPP7DPP8DPP4DPP9FAP
SCHEMBL6236021 0.80 ALOX15 (0.46) DPP7GSRDPP8DPP4DPP9
SCHEMBL6231881 0.79 DPP4 (0.33) DPP7DPP8DPP4DPP9FAP
SCHEMBL6231883 0.79 DPP4 (0.33) DPP7DPP8DPP4DPP9FAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6927290-B2 Production of mixed acid anhydride and amide compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-08-09 US disclosed
EP-1160236-B1 Production of mixed acid anhydride and amine compound SUMITOMO CHEMICAL CO (JP) 2005-05-25 EP disclosed
US-20040210059-A1 Production of mixed acid anhydride and amide compound SUMITOMO CHEMICAL COMPANY, LIMITED 2004-10-21 US disclosed
US-6753431-B2 REACTING A CARBAMATE DERIVATIVE WITH CARBOXYLIC AND HALOFORMIC ACID DERIVATIVES SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2004-06-22 US disclosed
US-20020032346-A1 Production of mixed acid anhydride and amide compound SUMITOMO CHEMICAL CO., LTD. 2002-03-14 US disclosed
EP-1160236-A2 Production of mixed acid anhydride and amine compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-12-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040210059-A1 Production of mixed acid anhydride and amide compound CA2, CA1, CA3 DPP7 4184/4885GSR 3817/4885DPP8 4391/4885
US-20020032346-A1 Production of mixed acid anhydride and amide compound CA2, CA1, CA3 DPP7 4184/4885GSR 3817/4885DPP8 4391/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.