SCHEMBL14569792

SCHEMBL14569792

COc1ccc(N(c2ccccc2)c2ccc(C=Cc3ccc4c(C#N)c5cc(C=Cc6ccc(N(c7ccccc7)c7ccc(OC)cc7)cc6)ccc5c(C#N)c4c3)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.48
RELA Q04206 5/20 0.43
TRPM8 Q7Z2W7 3/20 0.42
NFE2L2 Q16236 1/20 0.41
APP P05067 1/20 0.41
TUBB4A P04350 2/20 0.40
TUBB P07437 2/20 0.40
TUBA3C P0DPH7 2/20 0.40
TUBA1B P68363 2/20 0.40
TUBA4A P68366 2/20 0.40
TUBB4B P68371 2/20 0.40
TUBB3 Q13509 2/20 0.40
TUBB2A Q13885 2/20 0.40
TUBB8 Q3ZCM7 2/20 0.40
TUBA3E Q6PEY2 2/20 0.40
TUBA1A Q71U36 2/20 0.40
TUBA1C Q9BQE3 2/20 0.40
TUBB6 Q9BUF5 2/20 0.40
TUBB2B Q9BVA1 2/20 0.40
TUBB1 Q9H4B7 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12309967 0.99 TRPA1 (0.47) TRPA1RELATRPM8NFE2L2APP
SCHEMBL14079456 0.96 TRPA1 (0.45) TRPA1RELANFE2L2APPTUBB4A
SCHEMBL14569791 0.95 RELA (0.44) TRPA1RELANFE2L2APPTUBB4A
SCHEMBL14569523 0.92 SNCA (0.43) TRPA1RELATRPM8NFE2L2APP
SCHEMBL10075083 0.90 RELA (0.46) TRPA1RELATRPM8NFE2L2APP
SCHEMBL12309945 0.90 RELA (0.46) TRPA1RELATRPM8NFE2L2APP
SCHEMBL17883193 0.90 RELA (0.46) TRPA1RELATRPM8NFE2L2APP
SCHEMBL14569512 0.90 APP (0.40) RELAAPPCYP1A1CYP1A2CYP1B1
SCHEMBL14558901 0.89 TRPA1 (0.42) TRPA1RELATRPM8NFE2L2APP
SCHEMBL12309948 0.89 SNCA (0.41) TRPA1RELATRPM8TUBB4ATUBB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7196225-B2 Bis(aminostyryl) anthracene compound, synthesis intermediate thereof, and process for production thereof SONY CORPORATION (JP) 2007-03-27 US disclosed