SCHEMBL17883193

SCHEMBL17883193

COc1ccc(N(c2ccccc2)c2ccc(/C=C/c3ccc4c(C#N)c(C#N)c5ccc(C)cc5c4c3)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RELA Q04206 5/20 0.46
TRPA1 O75762 1/20 0.43
TRPM8 Q7Z2W7 3/20 0.39
NFE2L2 Q16236 1/20 0.37
APP P05067 1/20 0.37
MAPK10 P53779 1/20 0.37
TUBB1 Q9H4B7 3/20 0.36
TUBB4A P04350 2/20 0.36
TUBB P07437 2/20 0.36
TUBA3C P0DPH7 2/20 0.36
TUBA1B P68363 2/20 0.36
TUBA4A P68366 2/20 0.36
TUBB4B P68371 2/20 0.36
TUBB3 Q13509 2/20 0.36
TUBB2A Q13885 2/20 0.36
TUBB8 Q3ZCM7 2/20 0.36
TUBA3E Q6PEY2 2/20 0.36
TUBA1A Q71U36 2/20 0.36
TUBA1C Q9BQE3 2/20 0.36
TUBB6 Q9BUF5 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10075083 1.00 RELA (0.46) RELATRPA1TRPM8NFE2L2APP
SCHEMBL12309945 0.96 RELA (0.46) RELATRPA1TRPM8NFE2L2APP
SCHEMBL10022924 0.92 APP (0.38) RELATRPM8NFE2L2APPTUBB1
SCHEMBL12258663 0.90 RELA (0.40) RELATRPA1TRPM8NFE2L2APP
SCHEMBL14569792 0.90 TRPA1 (0.48) RELATRPA1TRPM8NFE2L2APP
SCHEMBL12309967 0.89 TRPA1 (0.47) RELATRPA1TRPM8NFE2L2APP
SCHEMBL12361853 0.88 RELA (0.44) RELATRPA1NFE2L2APPTUBB1
SCHEMBL10075344 0.87 APP (0.38) RELATRPM8NFE2L2APPTUBB1
SCHEMBL14079459 0.87 APP (0.38) RELATRPM8NFE2L2APPTUBB1
SCHEMBL12091217 0.87 APP (0.35) RELATRPM8APPTUBB1TUBB4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11873293-B2 Organic molecules for optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2024-01-16 US disclosed
US-11873293-B2 Organic molecules for optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2024-01-16 US disclosed
US-20230337538-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2023-10-19 US disclosed
US-20230337538-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2023-10-19 US disclosed
US-20230309398-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2023-09-28 US disclosed
US-20230309398-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2023-09-28 US disclosed
US-20230292615-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2023-09-14 US disclosed
US-20230292615-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2023-09-14 US disclosed
US-20230209847-A1 ORGANIC LIGHT EMITTING ELEMENT KYULUX, INC. (JP) 2023-06-29 US disclosed
US-20230159567-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-25 US disclosed
US-20230159567-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-25 US disclosed
US-20230119624-A1 COMPOSITION, FILM, ORGANIC LIGHT EMITTING ELEMENT, METHOD FOR PROVIDING LIGHT EMITTING COMPOSITION, AND PROGRAM KYULUX, INC. (JP) 2023-04-20 US disclosed
US-11384070-B2 Organic molecules for optoelectronic devices CYNORA GMBH (DE) 2022-07-12 US disclosed
US-20220123249-A1 ORGANIC LIGHT EMITTING ELEMENT KYULUX, INC. (JP) 2022-04-21 US disclosed
US-10862047-B2 Organic electroluminescent device KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2020-12-08 US disclosed
US-20200223831-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2020-07-16 US disclosed
US-10658596-B2 2020-05-19 US disclosed
US-20190177303-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2019-06-13 US disclosed
US-20160190478-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2016-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230292615-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES OR10J3, SALL4, RBP4 RELA 1930/4885TRPA1 2505/4885TRPM8 2820/4885
US-20230337538-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES OCIAD1, OCIAD2, OR10J3 RELA 465/4885TRPA1 18/4885TRPM8 72/4885
US-20230159567-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES OR10J3, OXER1, OXSR1 RELA 2132/4885TRPA1 404/4885TRPM8 401/4885
US-20200223831-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES XDH, OR10J3, C1S RELA 2746/4885TRPA1 914/4885TRPM8 1542/4885
US-11873293-B2 Organic molecules for optoelectronic devices XDH, C1S, OR10J3 RELA 2951/4885TRPA1 797/4885TRPM8 1645/4885
US-20230119624-A1 COMPOSITION, FILM, ORGANIC LIGHT EMITTING ELEMENT, METHOD FOR PROVIDING LIGHT EMITTING COMPOSITION, AND PROGRAM SOS1, MLLT1, ESYT2 RELA 3847/4885TRPA1 1066/4885TRPM8 1940/4885
US-11384070-B2 Organic molecules for optoelectronic devices XDH, C1S, OR10J3 RELA 2595/4885TRPA1 957/4885TRPM8 1753/4885
US-20190177303-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OR10J3, ORC3, OR51E2 RELA 3799/4885TRPA1 116/4885TRPM8 363/4885
US-20230309398-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES RXFP4, OR10J3, RXFP3 RELA 2685/4885TRPA1 747/4885TRPM8 1706/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.