Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28948998 | 0.94 | MEN1 (0.52) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL28948999 | 0.94 | MEN1 (0.52) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL10308499 | 0.94 | MEN1 (0.52) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL21097169 | 0.89 | PKM (0.39) | PKMCA2PPARD | |
| SCHEMBL10308500 | 0.89 | CYP3A4 (0.43) | TSHRCYP3A4PKMCA2 | |
| SCHEMBL14582791 | 0.88 | MEN1 (0.46) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL10308503 | 0.86 | ALDH1A1 (0.44) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL15807261 | 0.85 | CYP3A4 (0.40) | TSHRCYP3A4PKMCA2 | |
| SCHEMBL13471450 | 0.85 | CYP3A4 (0.40) | TSHRCYP3A4PKMCA2 | |
| SCHEMBL10308502 | 0.85 | CYP3A4 (0.40) | TSHRCYP3A4PKMCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7186826-B2 | Phosphorus-containing compounds and uses thereof | ARIAD GENE THERAPEUTICS, INC. (US) | 2007-03-06 | — | — | US | disclosed |