Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.35 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.33 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.33 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.33 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14392842 | 0.82 | MAOA (0.44) | MAOAMAOBKDM1ASLC6A3SLC6A4 | |
| SCHEMBL14392555 | 0.82 | MAOA (0.41) | MAOAMAOBKDM1ASLC6A3SLC6A4 | |
| SCHEMBL12134351 | 0.79 | SMN1; SMN2 (0.37) | MAOAMAOBSLC6A3SLC6A4SLC6A2 | |
| SCHEMBL14392715 | 0.78 | SLC6A3 (0.38) | MAOAMAOBKDM1ASLC6A3SLC6A4 | |
| SCHEMBL12134102 | 0.77 | MAPK1 (0.38) | MAOAMAOBKDM1ASLC6A3SLC6A4 | |
| SCHEMBL28612966 | 0.76 | MAOA (0.42) | MAOAMAOBKDM1ASLC6A3SLC6A4 | |
| SCHEMBL12134149 | 0.76 | L3MBTL1 (0.36) | MAOAMAOBSLC6A3SLC6A2 | |
| SCHEMBL12134272 | 0.75 | L3MBTL1 (0.47) | MAOAMAOBKDM4EALDH1A1TAAR1 | |
| SCHEMBL12134290 | 0.73 | TSHR (0.40) | SLC6A3SLC6A4SLC6A2ALDH1A1 | |
| SCHEMBL12134317 | 0.71 | SMN1; SMN2 (0.40) | MAOAMAOBSLC6A3SLC6A4OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7189863-B2 | Process for producing trifluoromethyl-substituted 2-alkoxyacetophenone derivatives | CENTRAL GLASS COMPANY, LIMITED (JP) | 2007-03-13 | — | — | US | disclosed |