Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | KDM4A | O75164 | 12/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 12/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.42 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.42 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Valeric Acid SCHEMBL148997 | 0.91 | ALDH1A1 (0.55) | ALDH1A1KDM4AKDM4CDNM1KDM5A | |
| Propionic Acid SCHEMBL145398 | 0.86 | ALDH1A1 (0.47) | ALDH1A1FFAR3KDM4AKDM4CDNM1 | |
| Butyric Acid SCHEMBL8168106 | 0.84 | FFAR3 (0.62) | ALDH1A1FFAR3HDAC3HDAC1HDAC2 | |
| Butyric Acid SCHEMBL3412203 | 0.82 | FFAR3 (0.59) | ALDH1A1FFAR3HDAC3HDAC1HDAC2 | |
| Butyric Acid SCHEMBL31040461 | 0.80 | ALDH1A1 (0.65) | ALDH1A1FFAR3HDAC3HDAC1HDAC2 | |
| Butyric Acid SCHEMBL2256290 | 0.80 | FFAR3 (0.68) | ALDH1A1FFAR3HDAC3HDAC1HDAC2 | |
| Octanoic Acid SCHEMBL5031491 | 0.79 | DNM1 (0.60) | ALDH1A1DNM1AKR1B1TSHRSLC22A6 | |
| Butyric Acid SCHEMBL15841789 | 0.79 | DNM1 (0.62) | ALDH1A1KDM4AKDM4CDNM1KDM5A | |
| Butyric Acid SCHEMBL4296264 | 0.79 | DNM1 (0.62) | ALDH1A1KDM4AKDM4CDNM1KDM5A | |
| Butyric Acid SCHEMBL4302171 | 0.79 | DNM1 (0.62) | ALDH1A1KDM4AKDM4CDNM1KDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058057-A1 | Anti-dandruff Agents | MERCK PATENT GMBH (DE) | 2012-03-08 | — | — | US | claimed |
| WO-2010136104-A2 | ANTI-DANDRUFF AGENTS | MERCK PATENT GMBH (DE) | 2010-12-02 | — | — | WO | claimed |
| US-20120058057-A1 | Anti-dandruff Agents | MERCK PATENT GMBH (DE) | 2012-03-08 | — | — | US | disclosed |
| WO-2010136104-A2 | ANTI-DANDRUFF AGENTS | MERCK PATENT GMBH (DE) | 2010-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058057-A1 | Anti-dandruff Agents | POLR1C, ETF1, PIK3C3 | ALDH1A1 272/4885FFAR3 1689/4885HDAC3 171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.