SCHEMBL462098

SCHEMBL462098

Cc1ccc(N(c2ccc(C)cc2)c2ccc(/C=C/c3ccc4ccc5cccc6ccc3c4c56)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 4/20 0.40
ALDH1A1 P00352 2/20 0.40
HPGD P15428 2/20 0.40
HSD17B10 Q99714 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
CYP3A4 P08684 1/20 0.40
TSHR P16473 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
GUSB P08236 2/20 0.40
FGF23 Q9GZV9 1/20 0.39
NFE2L2 Q16236 4/20 0.39
CYP1A2 P05177 1/20 0.36
NQO2 P16083 1/20 0.36
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
MAPT P10636 1/20 0.36
MAPK1 P28482 1/20 0.36
RAB9A P51151 1/20 0.36
KMT2A Q03164 1/20 0.36
RXFP1 Q9HBX9 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL462099 1.00 APP (0.40) APPALDH1A1HPGDHSD17B10L3MBTL1
SCHEMBL10050180 0.96 APP (0.46) APPALDH1A1HPGDHSD17B10L3MBTL1
SCHEMBL14570762 0.92 GUSB (0.37) APPALDH1A1HPGDHSD17B10L3MBTL1
SCHEMBL13897072 0.92 GUSB (0.38) APPALDH1A1HPGDHSD17B10L3MBTL1
SCHEMBL6153481 0.91 ALDH1A1 (0.47) ALDH1A1HPGDHSD17B10L3MBTL1CYP3A4
SCHEMBL6153484 0.91 ALDH1A1 (0.47) ALDH1A1HPGDHSD17B10L3MBTL1CYP3A4
SCHEMBL14570749 0.90 APP (0.40) APPALDH1A1HPGDHSD17B10L3MBTL1
SCHEMBL10050175 0.89 CHAT (0.39) APPALDH1A1HPGDHSD17B10L3MBTL1
SCHEMBL14570751 0.89 APP (0.48) APPALDH1A1HPGDHSD17B10L3MBTL1
SCHEMBL455790 0.89 APP (0.48) APPALDH1A1HPGDHSD17B10L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8809543-B2 Electrophotographic photoreceptor, electrophotographic image forming method, electrophotographic image forming apparatus, and process cartridge for electrophotographic image forming apparatus RICOH COMPANY, LTD. (JP) 2014-08-19 US disclosed
US-20120064443-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC IMAGE FORMING METHOD, ELECTROPHOTOGRAPHIC IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE FOR ELECTROPHOTOGRAPHIC IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2012-03-15 US disclosed
US-7507485-B2 Electrolytic cell; indium tin anode, hole injection layer containing phthalocyanine dye, passivation cathode; red illumination efficiency LG DISPLAY CO., LTD. (KR) 2009-03-24 US disclosed
US-7507485-B2 Electrolytic cell; indium tin anode, hole injection layer containing phthalocyanine dye, passivation cathode; red illumination efficiency LG DISPLAY CO., LTD. (KR) 2009-03-24 US disclosed
US-20070287083-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND METHOD OF PREPARING THE PHOTORECEPTOR, AND IMAGE FORMING APPARATUS, IMAGE FORMING METHOD AND PROCESS CARTRIDGE USING THE PHOTORECEPTOR RICOH COMPANY LTD. (JP) 2007-12-13 US disclosed
EP-0926557-B1 Electrophotographic photoreceptor, process for producing the same, and use of said photoreceptor for forming an image SHARP KK (JP) 2006-11-22 EP disclosed
EP-1063264-B1 Reaction product, process of producing same, electrophotographic photoconductor using same, electrophotographic apparatus having the photoconductor, and process cartridge for electrophotographic apparatus RICOH KK (JP) 2006-03-01 EP disclosed
US-20060014096-A1 Image forming method, image forming apparatus and process cartridge therefor RICOH COMPANY, LTD. (JP) 2006-01-19 US disclosed
US-6861188-B2 Electrophotographic photoreceptor, and image forming method, image forming apparatus and process cartridge therefor using the photoreceptor RICOH COMPANY LIMITED (JP) 2005-03-01 US disclosed
US-20030194627-A1 Electrophotographic photoreceptor, and image forming method, image forming apparatus and process cartridge therefor using the photoreceptor RICOH COMPANY LIMITED (JP) 2003-10-16 US disclosed
EP-1063264-A2 Reaction product, process of producing same, electrophotographic photoconductor using same, electrophotographic apparatus having the photoconductor, and process cartridge for electrophotographic apparatus Ricoh Company, Ltd. (JP) 2000-12-27 EP disclosed
US-6132914-A Bisazo compound and electrophotographic photoconductor using the same RICOH COMPANY, LTD. (JP) 2000-10-17 US disclosed
US-6103435-A A COMPOUND HAVING AN AZO CHARGE GENERATING MOIETY AND A TRIARYLAMINO CHARGE TRANSPORTING MOIETY IN THE MOLECULE RICOH COMPANY, LTD. (JP) 2000-08-15 US disclosed
US-6074792-A CHARGE TRANSPORT LAYER AND CHARGE GENERATING LAYER RICOH COMPANY, LTD. (JP) 2000-06-13 US disclosed
US-6068956-A CONTAINS AS A CHARGE GENERATION MATERIAL A PIGMENT INCLUDING A COMPOUND WITH A TETRAAZAPORPHYRIN SKELETON RICOH COMPANY, LTD. (JP) 2000-05-30 US disclosed
US-6054237-A ELECTROPHOTOGRAPHIC PHOTORECEPTOR WHERE THE CHARGE GENERATING LAYER COMPRISES A TAU-TYPE NONMETALLIC PHTHALOCYANINE HAVING ONE OR MORE PEAKS AT BRAGG'S ANGLE AND COPOLYMERS OF VINYL ACETATE-VINYL CHLORIDE; APPARATUS FOR INVERSION DEVELOPMENT SHARP KABUSHIKI KAISHA (JP) 2000-04-25 US disclosed
US-6030736-A PHOTOCONDUCTOR INCLUDES IN A TOP LAYER THEREOF A POLYSILOXANE MIXTURE SELECTED FROM AN UNMODIFIED POLYSILOXANE COMPOUND AND A MIXTURE OF AN UNMODIFIED POLYSILOXANE COMPOUND AND A METHACRYL OR VINYL OR ALKYL MODIFIED POLYSILOXANE RICOH COMPANY, LTD. (JP) 2000-02-29 US disclosed
US-5981124-A PHOTOCONDUCTIVE LAYER COMPRISES A COMPOUND CONTAINING AN AZO CHARGE GENERATING GROUP, A TRAIARYLAMINO CHARGE TRANSPORTING GROUP AND A BIVALENT COUPLER RICOH COMPANY, LTD. (JP) 1999-11-09 US disclosed
EP-0926557-A1 Electrophotographic photoreceptor, process for producing the same, and image forming apparatus using same Sharp Kabushiki Kaisha (JP) 1999-06-30 EP disclosed
US-5578405-A ELECTROCONDUCTIVE SUPPORT WITH ORGANIC PIGMENT LAYER FOR COPY MACHINE AND PRINTERS RICOH COMPANY (JP) 1996-11-26 US disclosed