Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9201393 | 0.81 | KDM4E (0.61) | GRM4KMT2ALMNASMN1; SMN2MEN1 | |
| SCHEMBL29384084 | 0.81 | GRM4 (0.50) | GRM4KMT2ALMNASMN1; SMN2MEN1 | |
| SCHEMBL2112699 | 0.81 | GRM4 (0.50) | GRM4KMT2ALMNASMN1; SMN2MEN1 | |
| SCHEMBL7776840 | 0.81 | GRM4 (0.50) | GRM4KMT2ALMNASMN1; SMN2MEN1 | |
| SCHEMBL28340763 | 0.77 | GRM4 (0.58) | GRM4KMT2ALMNASMN1; SMN2MEN1 | |
| SCHEMBL7470938 | 0.76 | GRM4 (0.53) | GRM4KMT2ALMNASMN1; SMN2MEN1 | |
| SCHEMBL3241147 | 0.74 | PKM (0.64) | GRM4KMT2ALMNASMN1; SMN2MEN1 | |
| SCHEMBL29128176 | 0.73 | GRM4 (0.58) | GRM4KMT2ALMNASMN1; SMN2MEN1 | |
| SCHEMBL9201385 | 0.73 | GRM4 (0.58) | GRM4KMT2ALMNASMN1; SMN2MEN1 | |
| SCHEMBL2321743 | 0.73 | OGG1 (0.62) | GRM4KMT2ALMNASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7186715-B2 | Piperazine- and piperidine-derivatives as melanocortin receptor agonists | ELI LILLY AND COMPANY (US) | 2007-03-06 | — | — | US | disclosed |