Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | WDR5 | P61964 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9201393 | 0.81 | KDM4E (0.61) | GRM4HPGDLMNAKMT2AMEN1 | |
| SCHEMBL14570782 | 0.81 | GRM4 (0.50) | GRM4HPGDLMNAKMT2AMEN1 | |
| SCHEMBL7776851 | 0.77 | L3MBTL1 (0.49) | HPGDLMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9201385 | 0.77 | GRM4 (0.58) | GRM4HPGDLMNAKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL17375204 | 0.77 | SMN1; SMN2 (0.59) | HPGDLMNASMN1; SMN2RAB9AMAPT | |
| SCHEMBL4093120 | 0.77 | WDR5 (0.50) | HPGDKMT2AMEN1SMN1; SMN2HTT | |
| SCHEMBL7784835 | 0.77 | AOC2 (0.54) | LMNAKMT2AMEN1SMN1; SMN2RAB9A | |
| SCHEMBL7470938 | 0.76 | GRM4 (0.53) | GRM4HPGDLMNAKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL6934265 | 0.76 | WDR5 (0.49) | HPGDKMT2AMEN1SMN1; SMN2HTT | |
| SCHEMBL3241147 | 0.74 | PKM (0.64) | GRM4HPGDLMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1142881-A1 | POLY(ADP-RIBOSE) POLYMERASE INHIBITORS CONSISTING OF PYRIMIDINE DERIVATIVES | MEIJI SEIKA KAISHA LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |