SCHEMBL145712

SCHEMBL145712

COc1ccc(C=CC(=O)Cl)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ F3 P13726 3/20 0.72
▸ THRB P10828 1/20 0.70
▸ ATM Q13315 1/20 0.70
▸ GSK3B P49841 2/20 0.68
▸ HDAC3 O15379 2/20 0.66
▸ HDAC1 Q13547 2/20 0.66
▸ HDAC2 Q92769 2/20 0.66
▸ HDAC8 Q9BY41 2/20 0.66
▸ HDAC6 Q9UBN7 2/20 0.66
▸ BACE1 P56817 1/20 0.62
▸ MAOB P27338 3/20 0.61
▸ MAOA P21397 2/20 0.61
▸ HDAC4 P56524 1/20 0.60
▸ HDAC7 Q8WUI4 1/20 0.60
▸ HDAC10 Q969S8 1/20 0.60
▸ HDAC11 Q96DB2 1/20 0.60
▸ HDAC9 Q9UKV0 1/20 0.60
▸ HDAC5 Q9UQL6 1/20 0.60
▸ BCHE P06276 1/20 0.60
▸ CYP3A4 P08684 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL145711 1.00 F3 (0.72) F3THRBATMGSK3BHDAC3
Toluene SCHEMBL16766953 0.89 RELA (0.61) F3THRBATMGSK3BHDAC3
Toluene SCHEMBL16766951 0.89 RELA (0.61) F3THRBATMGSK3BHDAC3
Ethyl Acetate SCHEMBL16774556 0.86 L3MBTL1 (0.56) F3THRBATMGSK3BHDAC3
Choline SCHEMBL11333783 0.85 GSK3B (0.55) F3THRBATMGSK3BHDAC3
4-Methoxycinnamic Acid SCHEMBL5330605 0.85 THRB (0.96) F3THRBATMGSK3BHDAC3
4-Methoxycinnamic Acid SCHEMBL5330596 0.85 THRB (0.96) F3THRBATMGSK3BHDAC3
SCHEMBL14331811 0.84 F3 (1.00) F3THRBATMGSK3BHDAC3
SCHEMBL9073433 0.84 F3 (0.78) F3THRBATMGSK3BHDAC3
SCHEMBL2744098 0.84 F3 (1.00) F3THRBATMGSK3BHDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 321 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250221904-A1 MILD, NATURAL, SOLID COMPOSITIONS FOR WATERLESS, SUSTAINABLE, SILICONE FREE COLOR AND UV PROTECTION FORMATS GALAXY SURFACTANTS LTD. (IN) 2025-07-10 — — US claimed
EP-4582077-A1 MILD, NATURAL, SOLID COMPOSITIONS FOR WATERLESS, SUSTAINABLE, SILICONE FREE COLOR AND UV PROTECTION FORMATS Galaxy Surfactants Ltd. (IN) 2025-07-09 — — EP claimed
CN-115490730-B Method for synthesizing selenium/sulfur ligand based on chiral BIDIME 安徽泽升科技有限公司 2023-04-21 — — CN claimed
CN-115490730-A Method for synthesizing selenium/sulfur ligand based on chiral BIDIME 安徽泽升科技有限公司 2022-12-20 — — CN claimed
CN-112600137-B Telescopic insulating trapping mechanism 国网浙江省电力有限公司龙游县供电公司 2022-05-17 — — CN claimed
CN-112653033-B Labor-saving insulating wire clamping device 国网浙江省电力有限公司龙游县供电公司 2022-04-08 — — CN claimed
CN-109718122-B Skin antioxidant whitening composition and preparation method thereof 派能生物科技(深圳)有限公司 2021-10-22 — — CN claimed
CN-111349068-A Organic synthesis method of scutellarein 中国药科大学 2020-06-30 — — CN claimed
JP-2011526420-A — — 2011-10-06 — — JP claimed
US-20110130522-A1 POLYMERISABLE COMPOUNDS FOR MAKING OPTO-ELECTRONIC DEVICES UNIVERSITEIT HASSELT (BE) 2011-06-02 — — US claimed
EP-2307398-A1 POLYMERISABLE COMPOUNDS FOR MAKING OPTO-ELECTRONIC DEVICES IMEC (BE) 2011-04-13 — — EP claimed
WO-2010000504-A1 POLYMERISABLE COMPOUNDS FOR MAKING OPTO-ELECTRONIC DEVICES INTERUNIVERSITAIR MICROELEKTRONICA CENTRUM (BE) 2010-01-07 — — WO claimed
US-5492836-A PERBENZOYLATION; CLEAVAGE BY CONTACTING WITH BROMOACETYL BROMIDE/WATER; GLYCOSIDATION; METHOXYCINNAMOYLATION; ANALYZING RESULTING BENZOATES THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1996-02-20 — — US claimed
EP-0218622-B1 AMIDES OF PARA-METHOXYCINNAMIC AND UTILIZATION THEREOF AS SOLAR FILTERS Robert, Dominique (FR) 1991-07-10 — — EP claimed
WO-1991007649-A1 METHOD FOR DETERMINING THE STRUCTURE OF OLIGOSACCHARIDE LINKAGES AND AUTOMATED INSTRUMENTATION THEREFOR THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1991-05-30 — — WO claimed
US-4791217-A SUNSCREEN AGENTS THAT DO NOT PENETRATE THE SKIN UNIVERSITE LOUIS PASTEUR (FR) 1988-12-13 — — US claimed
EP-0185066-B1 SULPHUR-CONTAINING DERIVATIVES OF PARA-METHOXYCINNAMIC ACID, PRODUCTION PROCESSES THEREOF, DERMO-PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING THEM AND APPLICATIONS UNIVERSITE LOUIS PASTEUR (STRASBOURG I) (FR) 1988-04-20 — — EP claimed
CN-122036500-A Preparation method of alkyl p-methoxy cinnamate 武汉能迈科香料有限公司 2026-05-15 — — CN disclosed
US-4013644-A [8 α(E), 13aβ]-5,8,13,13a-tetrahydro-2,3,10,11-tetramethoxy-8-(2-phenylethenyl)-6H-dibenzo[a,g]quinolizines and intermediates thereto G. D. SEARLE & CO. (US) 1977-03-22 — — US disclosed
US-4010191-A Acyl derivatives of substituted bis-arylalkylamino compounds DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) 1977-03-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250221904-A1 MILD, NATURAL, SOLID COMPOSITIONS FOR WATERLESS, SUSTAINABLE, SILICONE FREE COLOR AND UV PROTECTION FORMATS DOT1L, NSD3, NSD2 F3 2956/4885THRB 4272/4885ATM 824/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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