SCHEMBL14573166

SCHEMBL14573166

CCC(C)c1ccc([Si](OC)(OC)OC)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.42
TSHR P16473 2/20 0.42
GAA P10253 2/20 0.41
MAPT P10636 2/20 0.41
CYP2C9 P11712 1/20 0.39
USP2 O75604 1/20 0.38
PKM P14618 1/20 0.38
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38
HSD17B10 Q99714 1/20 0.38
LMNA P02545 1/20 0.38
TP53 P04637 1/20 0.38
ALOX12 P18054 1/20 0.38
NPBWR1 P48145 1/20 0.37
MCHR1 Q99705 1/20 0.37
KMT2A Q03164 2/20 0.36
RAB9A P51151 2/20 0.36
NPSR1 Q6W5P4 1/20 0.36
MEN1 O00255 1/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18014643 0.82 ALDH1A1 (0.41) ALDH1A1TSHRGAAMAPTCYP2C9
SCHEMBL15356152 0.82 ALDH1A1 (0.41) ALDH1A1TSHRGAAMAPTCYP2C9
SCHEMBL15356148 0.82 ALDH1A1 (0.41) ALDH1A1TSHRGAAMAPTCYP2C9
SCHEMBL20465902 0.81 ALDH1A1 (0.40) ALDH1A1TSHRGAAMAPTCYP2C9
SCHEMBL3110775 0.79 SMN1; SMN2 (0.39) ALDH1A1HPGDTP53NPBWR1MCHR1
SCHEMBL15417341 0.78 ESR1 (0.44) TSHRMAPTCYP2C9ALOX15LMNA
SCHEMBL598140 0.78 ALDH1A1 (0.52) ALDH1A1TSHRGAAMAPTCYP2C9
SCHEMBL15908036 0.77 ALDH1A1 (0.42) ALDH1A1TSHRGAAMAPTCYP2C9
SCHEMBL14648925 0.77 ALDH1A1 (0.42) ALDH1A1TSHRGAAMAPTCYP2C9
SCHEMBL5419641 0.76 SLC2A1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9971245-B2 Silicon-containing polymer, silicon-containing compound, composition for forming a resist under layer film, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-05-15 US disclosed
US-20170227690-A1 NEAR INFRARED RAY ABSORBENT COMPOSITION, NEAR INFRARED RAY CUT FILTER, SOLID IMAGE PICKUP ELEMENT, AND CAMERA MODULE FUJIFILM CORPORATION (JP) 2017-08-10 US disclosed
US-20170154766-A1 SILICON-CONTAINING CONDENSATE, COMPOSITION FOR FORMING A SILICON-CONTAINING RESIST UNDER LAYER FILM, AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-06-01 US disclosed
US-20160229939-A1 SILICON-CONTAINING POLYMER, SILICON-CONTAINING COMPOUND, COMPOSITION FOR FORMING A RESIST UNDER LAYER FILM, AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-08-11 US disclosed
US-9248693-B2 Patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-02-02 US disclosed
US-8992790-B2 Patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-03-31 US disclosed
US-8932953-B2 Composition for forming a silicon-containing resist underlayer film and patterning process using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-01-13 US disclosed
US-20140139925-A1 COPOLYMER, COMPOSITE PARTICLES CONTAINING COPOLYMER, OPTICAL MATERIAL CONTAINING COMPOSITE PARTICLES, AND OPTICAL ELEMENT CONTAINING OPTICAL MATERIAL CANON KABUSHIKI KAISHA (JP) 2014-05-22 US disclosed
US-20130284698-A1 PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-10-31 US disclosed
US-20130284699-A1 PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-10-31 US disclosed
US-7192683-B2 Planographic printing plate precursor FUJI PHOTO FILM CO., LTD (JP) 2007-03-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170227690-A1 NEAR INFRARED RAY ABSORBENT COMPOSITION, NEAR INFRARED RAY CUT FILTER, SOLID IMAGE PICKUP ELEMENT, AND CAMERA MODULE C9, SET, CRY1 ALDH1A1 2313/4885TSHR 3457/4885GAA 4214/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.