Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | ME2 | P23368 | 1/20 | 0.41 |
| ▸ | ME1 | P48163 | 1/20 | 0.41 |
| ▸ | ME3 | Q16798 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL175992 | 0.81 | CHRNA7 (0.58) | KDM4EALDH1A1TSHRUSP2ALOX15 | |
| SCHEMBL7423220 | 0.78 | OPRD1 (0.60) | MAPTCHRNA7HTR7SIGMAR1DRD2 | |
| SCHEMBL16312949 | 0.76 | NPC1 (0.49) | KDM4EALDH1A1TSHRUSP2ALOX15 | |
| SCHEMBL2899040 | 0.75 | LMNA (0.56) | KDM4EALDH1A1TSHRUSP2ALOX15 | |
| SCHEMBL19035644 | 0.75 | CHRNA7 (0.51) | KDM4EALDH1A1MAPTCHRNA7SIGMAR1 | |
| SCHEMBL17194427 | 0.75 | MAPT (0.51) | KDM4ESMN1; SMN2MAPTCHRNA7HTR7 | |
| SCHEMBL14573200 | 0.74 | CHRM4 (0.47) | CHRM4CHRM3TSHRMAPTCHRNA7 | |
| SCHEMBL14573192 | 0.73 | KDM4E (0.47) | KDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL458240 | 0.73 | OPRD1 (0.59) | KDM4EUSP2SIGMAR1TMEM97NPC1 | |
| SCHEMBL6550226 | 0.71 | MAPT (0.61) | KDM4EALDH1A1USP2ALOX15SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183367-B2 | Vinyl sulphone modified polymer | N.V. ORGANON (NL) | 2007-02-27 | — | — | US | disclosed |
| US-7183367-B2 | Vinyl sulphone modified polymer | N.V. ORGANON (NL) | 2007-02-27 | — | — | US | disclosed |