Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14573267 | 0.80 | ALDH1A1 (0.51) | KDM4ECYP1A2LMNAPOLBALDH1A1 | |
| SCHEMBL25213658 | 0.80 | BACE1 (0.37) | KDM4ECYP2C19CYP3A4HIF1ARXFP1 | |
| SCHEMBL3837501 | 0.80 | CRHBP (0.39) | KDM4ECYP2C19CYP3A4HIF1ARXFP1 | |
| SCHEMBL11985968 | 0.78 | POLB (0.40) | KDM4ECYP2C19CYP3A4HIF1ARXFP1 | |
| SCHEMBL3844688 | 0.77 | KDM4E (0.44) | KDM4ECYP2C19CYP3A4HIF1ALMNA | |
| SCHEMBL10746163 | 0.77 | CYP2C19 (0.39) | KDM4ECYP2C19CYP3A4HIF1ARXFP1 | |
| SCHEMBL1133977 | 0.77 | NT5E (0.34) | KDM4ECYP2C19CYP3A4HIF1AESR1 | |
| SCHEMBL25083068 | 0.77 | IMPDH2 (0.42) | KDM4ECYP2C19CYP3A4HIF1ACYP1A2 | |
| SCHEMBL1134024 | 0.77 | CYP19A1 (0.40) | POLBALDH1A1NPC1MAPT | |
| Hydrochloric Acid SCHEMBL4504877 | 0.76 | KDM4E (0.43) | KDM4ECYP2C19CYP3A4HIF1ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947856-A | EZH2 inhibitor and preparation method and application thereof | 星希尔生物科技(上海)有限公司 | 2023-10-27 | — | — | CN | disclosed |
| US-7186840-B2 | Quinoline derivatives as anti-inflammatory agents | ROCHE PALO ALTO LLC (US) | 2007-03-06 | — | — | US | disclosed |