SCHEMBL11911278

SCHEMBL11911278

COc1ccc(OC(=O)c2ccc(C(C)=O)cc2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.66
▸ CYP1A2 P05177 1/20 0.66
▸ CYP2C9 P11712 1/20 0.66
▸ CYP2C19 P33261 1/20 0.66
▸ SMN1; SMN2 Q16637 1/20 0.66
▸ KMT2A Q03164 9/20 0.64
▸ CA1 P00915 3/20 0.62
▸ CA2 P00918 3/20 0.62
▸ MAPT P10636 5/20 0.61
▸ GFER P55789 1/20 0.61
▸ PRSS1 P07477 1/20 0.61
▸ ACR P10323 1/20 0.61
▸ HPGD P15428 1/20 0.55
▸ RAB9A P51151 1/20 0.55
▸ CES2 O00748 1/20 0.55
▸ CES1 P23141 1/20 0.55
▸ KDM4E B2RXH2 1/20 0.54
▸ ALDH1A1 P00352 1/20 0.54
▸ GLA P06280 1/20 0.53
▸ TSHR P16473 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2742858 0.95 LMNA (0.60) LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2
SCHEMBL11911280 0.95 MAPT (0.66) LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2
SCHEMBL12376950 0.95 MAPT (0.66) LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2
SCHEMBL12376951 0.95 LMNA (0.60) LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2
SCHEMBL12376956 0.95 MAPT (0.66) LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2
SCHEMBL15854280 0.95 LMNA (0.60) LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2
SCHEMBL19763411 0.95 MAPT (0.66) LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2
SCHEMBL4329847 0.95 LMNA (0.60) LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2
SCHEMBL12608584 0.92 LMNA (0.75) LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2
SCHEMBL12633724 0.92 LMNA (0.75) LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8231947-B2 Oilfield elements having controlled solubility and methods of use SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2012-07-31 — — US disclosed
US-7888450-B2 Liquid crystal polymer and film thereof FUJIFILM CORPORATION (JP) 2011-02-15 — — US disclosed
US-20090240022-A1 LIQUID CRYSTAL POLYMER AND FILM THEREOF FUJIFILM CORPORATION (JP) 2009-09-24 — — US disclosed
US-20070224151-A1 Cosmetic Composition Comprising at Least One Specific Block Copolymer L'OREAL (FR) 2007-09-27 — — US disclosed
US-20070172505-A1 Cosmetic composition comprising at least one specific block copolymer LOREAL (FR) 2007-07-26 — — US disclosed
US-20070107908-A1 Oilfield Elements Having Controlled Solubility and Methods of Use SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2007-05-17 — — US disclosed
US-7217295-B2 Use of soluble conductive polymers for treating human keratin fibers L'OREAL S.A. (FR) 2007-05-15 — — US disclosed
US-7175955-B2 Electrophotographic photoreceptor, electrophotographic process cartridge and image forming apparatus FUJI XEROX CO., LTD. (JP) 2007-02-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070172505-A1 Cosmetic composition comprising at least one specific block copolymer COIL, CRYAB, TBCB LMNA 697/4885CYP1A2 1295/4885CYP2C9 1654/4885
US-20070224151-A1 Cosmetic Composition Comprising at Least One Specific Block Copolymer FABP4, HSD17B4, LRBA LMNA 1377/4885CYP1A2 1027/4885CYP2C9 1535/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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