Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | GSR | P00390 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16956334 | 0.86 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2ATSHRTDP1 | |
| SCHEMBL8927601 | 0.86 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AHSP90AA1TSHR | |
| SCHEMBL2366617 | 0.83 | ERN1 (0.49) | ALDH1A1MEN1KMT2AHSP90AA1TSHR | |
| SCHEMBL16957201 | 0.81 | MEN1 (0.43) | ALDH1A1MEN1KMT2AHSP90AA1TSHR | |
| SCHEMBL670917 | 0.80 | TSHR (0.58) | ALDH1A1MEN1KMT2AHSP90AA1TSHR | |
| SCHEMBL9422617 | 0.79 | GPR35 (0.53) | ALDH1A1MEN1KMT2ATSHRTDP1 | |
| SCHEMBL5211004 | 0.79 | ERN1 (0.49) | ALDH1A1MEN1KMT2ATSHRTDP1 | |
| SCHEMBL2907461 | 0.78 | TSHR (0.44) | ALDH1A1MEN1KMT2ATSHRTDP1 | |
| SCHEMBL16961852 | 0.78 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AHSP90AA1TSHR | |
| SCHEMBL11048252 | 0.78 | MEN1 (0.40) | ALDH1A1MEN1KMT2ATSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113509959-A | Preparation method of hollow mesoporous nano silicon spheres for packaging chiral catalyst, product and application thereof | 重庆邮电大学 | 2021-10-19 | — | — | CN | disclosed |
| CN-103269592-B | Cyclic amine substituted oxazolidinone CETP inhibitors | MERCK SHARP & DOHME CORP. (US) | 2016-05-11 | — | — | CN | disclosed |
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |
| WO-2011029956-A1 | FLAVONES AND FLAVANONES DERIVATES AS DNA METHYLTRANSFERASES INHIBITORS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2011-03-17 | — | — | WO | disclosed |
| US-4119646-A | Hexahydrobenzofuranone compounds | MOBIL OIL CORPORATION (US) | 1978-10-10 | — | — | US | disclosed |
| US-4011239-A | MANGANESE, VANADIUM, CERIUM | MOBIL OIL CORPORATION (US) | 1977-03-08 | — | — | US | disclosed |