Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16956334 | 0.86 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1TDP1ERN1 | |
| SCHEMBL29954426 | 0.83 | ERN1 (0.49) | MEN1KMT2AUSP2KEAP1NFE2L2 | |
| SCHEMBL11551067 | 0.80 | TDP1 (0.52) | MEN1KMT2AUSP2KEAP1NFE2L2 | |
| SCHEMBL3390153 | 0.80 | TDP1 (0.52) | MEN1KMT2AUSP2KEAP1NFE2L2 | |
| SCHEMBL9422617 | 0.79 | GPR35 (0.53) | MEN1KMT2AALDH1A1TDP1ERN1 | |
| SCHEMBL5211004 | 0.79 | ERN1 (0.49) | MEN1KMT2AALDH1A1TDP1ERN1 | |
| SCHEMBL1458014 | 0.78 | ALDH1A1 (0.55) | MEN1KMT2AALDH1A1TDP1ERN1 | |
| SCHEMBL16961852 | 0.78 | ALDH1A1 (0.39) | MEN1KMT2AALDH1A1TDP1ERN1 | |
| SCHEMBL2402265 | 0.78 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1TDP1ERN1 | |
| SCHEMBL31154187 | 0.78 | GPR35 (0.56) | MEN1KMT2AALDH1A1TDP1ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113831272-B | Method for synthesizing 2-substituted indole compound by palladium-catalyzed iodobenzene and oxime ester | 华南理工大学 | 2023-07-18 | — | — | CN | disclosed |
| CN-113831272-A | Method for synthesizing 2-substituted indole compound by using palladium to catalyze iodobenzene and oxime ester | 华南理工大学 | 2021-12-24 | — | — | CN | disclosed |
| US-4454337-A | Semicarbazide intermediates for preparing 4-substituted indoles | SMITHKLINE BECKMAN CORPORATION (US) | 1984-06-12 | — | — | US | disclosed |
| US-4394514-A | Processes for preparing 4-substituted indoles | SMITHKLINE BECKMAN CORPORATION (US) | 1983-07-19 | — | — | US | disclosed |
| US-3979410-A | Intermediate α-acyl-β-dialkylamino-2-nitrostyrenes | HOFFMANN-LA ROCHE INC. (US) | 1976-09-07 | — | — | US | disclosed |
| US-3979410-A | Intermediate α-acyl-β-dialkylamino-2-nitrostyrenes | HOFFMANN-LA ROCHE INC. (US) | 1976-09-07 | — | — | US | disclosed |
| US-3931225-A | Process for preparing o-nitrobenzylketones | HOFFMANN-LA ROCHE INC. (US) | 1976-01-06 | — | — | US | disclosed |
| US-3931225-A | Process for preparing o-nitrobenzylketones | HOFFMANN-LA ROCHE INC. (US) | 1976-01-06 | — | — | US | disclosed |