Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | MDM4 | O15151 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15929330 | 1.00 | CASP3 (0.54) | CASP3KMT2AEPHX2MDM4TP53 | |
| SCHEMBL29445597 | 1.00 | CASP3 (0.54) | CASP3KMT2AEPHX2MDM4TP53 | |
| SCHEMBL15223382 | 0.91 | CASP3 (0.53) | CASP3KMT2AEPHX2MDM4TP53 | |
| SCHEMBL31453048 | 0.91 | CASP3 (0.53) | CASP3KMT2AEPHX2MDM4TP53 | |
| SCHEMBL29445616 | 0.89 | CASP3 (0.51) | CASP3KMT2AEPHX2MDM4TP53 | |
| SCHEMBL13652772 | 0.89 | CASP3 (0.51) | CASP3KMT2AEPHX2MDM4TP53 | |
| SCHEMBL3269193 | 0.87 | CASP3 (0.56) | CASP3KMT2AEPHX2MDM4TP53 | |
| SCHEMBL13452269 | 0.87 | CASP3 (0.56) | CASP3KMT2AEPHX2MDM4TP53 | |
| SCHEMBL31068390 | 0.87 | CASP3 (0.56) | CASP3KMT2AEPHX2MDM4TP53 | |
| SCHEMBL5021152 | 0.87 | CASP3 (0.56) | CASP3KMT2AEPHX2MDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3524273-A1 | CYSTEINE MODIFIED ANTIBODY-DRUG CONJUGATE AND PREPARATION METHOD THEREOF | Sichuan Baili Pharm Co., Ltd. (CN) | 2019-08-14 | — | — | EP | disclosed |
| EP-3520817-A1 | DRUG-CONJUGATES, CONJUGATION METHODS, AND USES THEREOF | Concortis Biosystems, Corp (US) | 2019-08-07 | — | — | EP | disclosed |
| EP-1083980-B1 | MODULATION OF MOLECULAR INTERACTION SITES ON RNA AND OTHER BIOMOLECULES | ISIS PHARMACEUTICALS INC (US) | 2007-03-21 | — | — | EP | disclosed |