SCHEMBL3269193

SCHEMBL3269193

C[C@@H](C=O)NC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.59

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ CASP3 P42574 4/20 0.56
▸ KMT2A Q03164 2/20 0.53
▸ EPHX2 P34913 1/20 0.50
▸ MDM4 O15151 2/20 0.47
▸ TP53 P04637 2/20 0.47
▸ PIN1 Q13526 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31068390 1.00 CASP3 (0.56) CASP3KMT2AEPHX2MDM4TP53
SCHEMBL13452269 1.00 CASP3 (0.56) CASP3KMT2AEPHX2MDM4TP53
SCHEMBL29952701 1.00 CASP3 (0.56) CASP3KMT2AEPHX2MDM4TP53
SCHEMBL5021152 1.00 CASP3 (0.56) CASP3KMT2AEPHX2MDM4TP53
SCHEMBL15382522 0.88 CASP3 (0.55) CASP3KMT2AEPHX2MDM4TP53
SCHEMBL15929330 0.87 CASP3 (0.54) CASP3KMT2AEPHX2MDM4TP53
SCHEMBL14581384 0.87 CASP3 (0.54) CASP3KMT2AEPHX2MDM4TP53
SCHEMBL29445597 0.87 CASP3 (0.54) CASP3KMT2AEPHX2MDM4TP53
SCHEMBL2625076 0.86 KMT2A (0.58) CASP3KMT2AEPHX2MDM4TP53
SCHEMBL31453048 0.86 CASP3 (0.53) CASP3KMT2AEPHX2MDM4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112386707-B Tumor targeting polypeptide drug conjugate and preparation method thereof 辽宁医学诊疗科技研发中心有限公司 2023-08-11 — — CN claimed
US-20260109743-A1 PYY3-36 Analog and Use Thereof in Treating Disease SUN TAO (CN) 2026-04-23 — — US disclosed
US-20260098071-A1 GLP-1 Analog and Use Thereof in Treatment of GLP-1 Related Diseases SUN TAO (CN) 2026-04-09 — — US disclosed
EP-4482583-B1 ZWITTERIONIC ANTIBACTERIAL COMPOUNDS HOFFMANN LA ROCHE (CH) 2026-04-01 — — EP disclosed
US-12492225-B2 Melanocyte-regulating peptides IDP DISCOVERY PHARMA, S.L. (ES) 2025-12-09 — — US disclosed
WO-2025229308-A1 CONJUGATE FOR TREATING REPEAT EXPANSION DISORDERS OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2025-11-06 — — WO disclosed
EP-4590423-A1 METHODS AND PLATFORM FOR CHEMICAL SYNTHESIS The University Court Of The University Of Glasgow (GB) 2025-07-30 — — EP disclosed
US-20250186360-A1 LIQUID-LIQUID PHASE SEPARATION (LLPS)-BASED COMPARTMENTS COMPRISING A SHORT PEPTIDE AND AN ANIONIC POLYMER RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) 2025-06-12 — — US disclosed
EP-4532513-A1 CYCLIC PEPTIDES WITH ANTIBACTERIAL ACTIVITY AGAINST MULTIDRUG RESISTANT (MDR) PATHOGENS Fundación Privada Instituto De Salud Global Barcelona (ES) 2025-04-09 — — EP disclosed
CN-119451974-A Cyclic peptides having antibacterial activity against Multiple Drug Resistant (MDR) pathogens 巴塞罗那全球健康研究所私人基金会 2025-02-14 — — CN disclosed
US-20120115783-A1 PEPTIDOMIMETIC MACROCYCLES Alleron therapeutics, Inc (US) 2012-05-10 — — US disclosed
US-20120115793-A1 PEPTIDOMIMETIC MACROCYCLES Alleron therapeutics, Inc (US) 2012-05-10 — — US disclosed
US-7968548-B2 Agonist or antgonist and binders and inversion of agonist; use in the treatment of metabolic, immune, infection-related and melanocortin receptor mediated disorders including specifically treatment of obesity and related conditions PALATIN TECHNOLOGIES, INC. (US) 2011-06-28 — — US disclosed
WO-2011069063-A2 MULTICYCLIC COMPOUNDS AND METHODS OF USE THEREOF SUNOVION PHARMACEUTICALS, INC. (US) 2011-06-09 — — WO disclosed
WO-2011047215-A1 IMPROVED PEPTIDOMIMETIC MACROCYCLES AILERON THERAPEUTICS, INC. (US) 2011-04-21 — — WO disclosed
US-20100286024-A1 Insulinotropic compounds and uses thereof ACTIVOTEC SPP LIMITED (GB) 2010-11-11 — — US disclosed
US-20100168443-A1 Ethoid-Containing Compounds, Methods for Preparing Ethoid-Containing Compounds, and Methods of Use UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2010-07-01 — — US disclosed
EP-1943275-B1 INSULINOTROPIC COMPOUNDS AND USES THEREOF ACTIVOTEC SPP LTD (GB) 2010-06-16 — — EP disclosed
US-7727991-B2 Substituted melanocortin receptor-specific single acyl piperazine compounds PALATIN TECHNOLOGIES, INC. (US) 2010-06-01 — — US disclosed
US-20070179100-A1 Protected monomers ALNYLAM PHARMACEUTICALS, INC. 2007-08-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12492225-B2 Melanocyte-regulating peptides MC1R, MITF, MCHR1 CASP3 4704/4885KMT2A 995/4885EPHX2 3556/4885
US-20100286024-A1 Insulinotropic compounds and uses thereof GLP1R, GPR119, IAPP CASP3 2297/4885KMT2A 3871/4885EPHX2 2576/4885
US-20260109743-A1 PYY3-36 Analog and Use Thereof in Treating Disease NPY1R, NPY4R, NPY2R CASP3 2490/4885KMT2A 1512/4885EPHX2 3466/4885
US-20120115793-A1 PEPTIDOMIMETIC MACROCYCLES GLP1R, PROKR1, VIP CASP3 1026/4885KMT2A 4189/4885EPHX2 3191/4885
US-20120115783-A1 PEPTIDOMIMETIC MACROCYCLES GLP1R, PROKR1, VIP CASP3 1026/4885KMT2A 4189/4885EPHX2 3191/4885
US-20260098071-A1 GLP-1 Analog and Use Thereof in Treatment of GLP-1 Related Diseases GLP1R, GPR119, HTR1F CASP3 2963/4885KMT2A 766/4885EPHX2 2628/4885
US-20070179100-A1 Protected monomers PCNA, POLN, PARP1 CASP3 1082/4885KMT2A 1569/4885EPHX2 4321/4885
US-20100168443-A1 Ethoid-Containing Compounds, Methods for Preparing Ethoid-Containing Compounds, and Methods of Use PARG, POLH, PHOSPHO1 CASP3 3633/4885KMT2A 1221/4885EPHX2 97/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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