SCHEMBL29445597

SCHEMBL29445597

CC(C)[C@@H](C=O)NC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.57

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ CASP3 P42574 4/20 0.54
▸ KMT2A Q03164 2/20 0.51
▸ EPHX2 P34913 1/20 0.48
▸ MDM4 O15151 2/20 0.46
▸ TP53 P04637 2/20 0.46
▸ PIN1 Q13526 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15929330 1.00 CASP3 (0.54) CASP3KMT2AEPHX2MDM4TP53
SCHEMBL14581384 1.00 CASP3 (0.54) CASP3KMT2AEPHX2MDM4TP53
SCHEMBL15223382 0.91 CASP3 (0.53) CASP3KMT2AEPHX2MDM4TP53
SCHEMBL31453048 0.91 CASP3 (0.53) CASP3KMT2AEPHX2MDM4TP53
SCHEMBL29445616 0.89 CASP3 (0.51) CASP3KMT2AEPHX2MDM4TP53
SCHEMBL13652772 0.89 CASP3 (0.51) CASP3KMT2AEPHX2MDM4TP53
SCHEMBL3269193 0.87 CASP3 (0.56) CASP3KMT2AEPHX2MDM4TP53
SCHEMBL13452269 0.87 CASP3 (0.56) CASP3KMT2AEPHX2MDM4TP53
SCHEMBL31068390 0.87 CASP3 (0.56) CASP3KMT2AEPHX2MDM4TP53
SCHEMBL5021152 0.87 CASP3 (0.56) CASP3KMT2AEPHX2MDM4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112386707-B Tumor targeting polypeptide drug conjugate and preparation method thereof 辽宁医学诊疗科技研发中心有限公司 2023-08-11 — — CN claimed
US-20260078144-A1 ACTIVE PEPTIDE, AND COMPOSITION AND USE THEREOF WINKEY TECH USA INC (US) 2026-03-19 — — US disclosed
EP-4706670-A1 PSD-95 DOMAIN INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF Shenzhen Salubris Pharmaceuticals Co., Ltd. (CN) 2026-03-11 — — EP disclosed
US-12492225-B2 Melanocyte-regulating peptides IDP DISCOVERY PHARMA, S.L. (ES) 2025-12-09 — — US disclosed
EP-4650362-A1 NEUROPROTECTIVE PSD-95 POLYPEPTIDE INHIBITOR AND USE THEREOF Beijing Tuo Jie Biopharmaceutical Co. Ltd. (CN) 2025-11-19 — — EP disclosed
US-20250186360-A1 LIQUID-LIQUID PHASE SEPARATION (LLPS)-BASED COMPARTMENTS COMPRISING A SHORT PEPTIDE AND AN ANIONIC POLYMER RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) 2025-06-12 — — US disclosed
EP-4532513-A1 CYCLIC PEPTIDES WITH ANTIBACTERIAL ACTIVITY AGAINST MULTIDRUG RESISTANT (MDR) PATHOGENS Fundación Privada Instituto De Salud Global Barcelona (ES) 2025-04-09 — — EP disclosed
CN-115746097-B Antibacterial peptide AS-12W and preparation method and application thereof 中国药科大学 2025-03-21 — — CN disclosed
US-20250092087-A1 THIOAMIDE ANALOGUES OF PEPTIDE ANTIGENS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2025-03-20 — — US disclosed
CN-119451974-A Cyclic peptides having antibacterial activity against Multiple Drug Resistant (MDR) pathogens 巴塞罗那全球健康研究所私人基金会 2025-02-14 — — CN disclosed
CN-114573686-A Polypeptide containing disulfide bond and having serine protease activity inhibition function and application thereof 中国医学科学院药物研究所 2022-06-03 — — CN disclosed
WO-2022111713-A1 POLYPEPTIDE CONTAINING DISULFIDE BONDS AND CAPABLE OF INHIBITING ACTIVITY OF SERINE PROTEASE, DERIVED HYBRID PEPTIDE THEREOF, AND USE THEREOF 中国医学科学院药物研究所 2022-06-02 — — WO disclosed
WO-2022106825-A1 COMPOSITIONS UNIVERSITY OF SOUTHAMPTON (GB) 2022-05-27 — — WO disclosed
EP-3986439-A1 COMPOSITIONS AND METHODS USEFUL IN TREATING BRAIN DISEASES University of Kansas (US) 2022-04-27 — — EP disclosed
EP-3986914-A1 CONSTRAINED PEPTIDES TearSolutions, Inc. (US) 2022-04-27 — — EP disclosed
CN-109678944-B Antibacterial polypeptide HF-18 and preparation method and application thereof 中国药科大学 2022-04-26 — — CN disclosed
CN-106866793-B Polypeptide compound and preparation method and application thereof 韩苏 2022-04-19 — — CN disclosed
CN-114245800-A Melanocyte regulatory peptides IDP研发制药有限公司 2022-03-25 — — CN disclosed
US-11279734-B2 Solution-phase affinity selection of inhibitors from combinatorial peptide libraries MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2022-03-22 — — US disclosed
CN-114206916-A Restricted peptides 缇尔索卢森公司 2022-03-18 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12492225-B2 Melanocyte-regulating peptides MC1R, MITF, MCHR1 CASP3 4704/4885KMT2A 995/4885EPHX2 3556/4885
US-20250092087-A1 THIOAMIDE ANALOGUES OF PEPTIDE ANTIGENS TAP1, TAP2, DNPEP CASP3 1991/4885KMT2A 2242/4885EPHX2 3241/4885
US-20260078144-A1 ACTIVE PEPTIDE, AND COMPOSITION AND USE THEREOF ARGLU1, ARG1, POT1 CASP3 2153/4885KMT2A 1602/4885EPHX2 4180/4885
US-11279734-B2 Solution-phase affinity selection of inhibitors from combinatorial peptide libraries TP53, MDM2, MDM4 CASP3 2615/4885KMT2A 3182/4885EPHX2 3865/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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