Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | TK1 | P04183 | 1/20 | 0.34 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.34 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.34 |
| ▸ | PNP | P00491 | 2/20 | 0.33 |
| ▸ | POLA1 | P09884 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HINT1 | P49773 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14620703 | 0.88 | ADORA3 (0.47) | HPGDADORA3TK1PNPUSP2 | |
| SCHEMBL16258667 | 0.88 | ADORA3 (0.47) | HPGDADORA3TK1PNPUSP2 | |
| SCHEMBL13626438 | 0.88 | ADORA3 (0.47) | HPGDADORA3TK1PNPUSP2 | |
| SCHEMBL116166 | 0.88 | ADORA3 (0.47) | HPGDADORA3TK1PNPUSP2 | |
| SCHEMBL18537401 | 0.88 | ADORA3 (0.47) | HPGDADORA3TK1PNPUSP2 | |
| SCHEMBL18537395 | 0.88 | ADORA3 (0.47) | HPGDADORA3TK1PNPUSP2 | |
| Hydrochloric Acid SCHEMBL5972616 | 0.87 | ADORA3 (0.46) | HPGDADORA3TK1PNPUSP2 | |
| Water SCHEMBL28222138 | 0.87 | ADORA3 (0.46) | HPGDADORA3TK1PNPUSP2 | |
| SCHEMBL27523643 | 0.82 | TK1 (0.47) | HPGDADORA3TK1PNPUSP2 | |
| SCHEMBL30765431 | 0.82 | ADORA3 (0.44) | HPGDPAX8ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070037773-A1 | Methods and compositions for treating flaviviruses and pestiviruses | IDENIX PHARMACEUTICALS LLC | 2007-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037773-A1 | Methods and compositions for treating flaviviruses and pestiviruses | MTAP, PHOSPHO1, PNP | HPGD 2320/4885PAX8 3667/4885ADORA3 1821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.